Development and validation of CYP26A1 inhibition assay for high-throughput screening

Dataset for Sakamuru, S., Ma, D., Pierro, J. D., Baker, N. C., Kleinstreuer, N., Cali, J. J., Knudsen, T. B., & Xia, M. (2024). Development and validation of CYP26A1 inhibition assay for high-throughput screening. Biotechnology Journal, 19, e2300659. https://doi.org/10.1002/biot.202300659. This dataset is not publicly accessible because: Non-EPA generated data, cross partner project with the National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD (NCATS) and National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods, National Institute of Environmental Health Sciences, National Institutes of Health, RTP NC. The data were generated by NCATS. It can be accessed through the following means: Data will be made available upon request from Menghang Xia (NCATS, National Institutes of Health) email mxia@mail.nih.gov. Format: Not available. This dataset is associated with the following publication: Sakamuru, S., D. Ma, J. Pierro, N. Baker, N. Kleinstreuer, J. Cali, T. Knudsen, and M. Xia. Development and Validation of CYP26A1 Inhibition Assay for High-Throughput Screening. Biotechnology Journal. John Wiley & Sons, Inc., Hoboken, NJ, USA, 19(6): 2300659, (2024).

                                            [
  "020:00"
]
                                        

                                            {
  "fn": "Thomas Knudsen",
  "hasEmail": "mailto:knudsen.thomas@epa.gov"
}
                                        

                                            []
                                        

                                            [
  "CYP26",
  "all-trans retinoic acid (atRA)",
  "bioactivity",
  "cytochrome P450 (CYP)",
  "high-throughput screening",
  "retinoic acid receptor (RAR)"
]
                                        

                                            [
  "020:000"
]
                                        

                                            {
  "name": "U.S. EPA Office of Research and Development (ORD)",
  "subOrganizationOf": {
    "name": "U.S. Environmental Protection Agency",
    "subOrganizationOf": {
      "name": "U.S. Government"
    }
  }
}
                                        

                                            [
  "https://doi.org/10.1002/biot.202300659",
  "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11338008"
]
                                        

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