Judson_Kleinstreuer_Development and Validation of a Computational Model for Androgen Receptor Activity.
Data on 1855 chemicals were generated during ToxCast Phases I and II and Tox21 screening using 11 AR-related in vitro assays to build a computational network model for AR pathway activity.
This dataset is associated with the following publication:
Kleinstreuer, N.C., P. Ceger, E. Watt, M. Martin, K. Houck, P. Browne, R. Thomas, W. Casey, D. Dix, D. Allen, S. Sakamuru, M. Xia, R. Huang, and R. Judson. (Chemical Research in Toxicology) Development and Validation of a Computational Model for Androgen Receptor Activity. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, USA, 30(4): 946-964, (2017).
Complete Metadata
| accessLevel | public |
|---|---|
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Richard Judson",
"hasEmail": "mailto:judson.richard@epa.gov"
}
|
| description | Data on 1855 chemicals were generated during ToxCast Phases I and II and Tox21 screening using 11 AR-related in vitro assays to build a computational network model for AR pathway activity. This dataset is associated with the following publication: Kleinstreuer, N.C., P. Ceger, E. Watt, M. Martin, K. Houck, P. Browne, R. Thomas, W. Casey, D. Dix, D. Allen, S. Sakamuru, M. Xia, R. Huang, and R. Judson. (Chemical Research in Toxicology) Development and Validation of a Computational Model for Androgen Receptor Activity. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, USA, 30(4): 946-964, (2017). |
| distribution |
[
{
"title": "https://gaftp.epa.gov/Comptox/Staff/rjudson/publications/Kleinstreuer%20AR%20model%20CRT%202016/",
"accessURL": "https://gaftp.epa.gov/Comptox/Staff/rjudson/publications/Kleinstreuer%20AR%20model%20CRT%202016/"
}
]
|
| identifier | https://doi.org/10.23719/1503692 |
| keyword |
[
"ACToR",
"High throughput screening",
"ToxCast",
"androgen receptor pathway",
"computational model",
"endocrine disruption screening"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2019-04-08 |
| programCode |
[
"020:095"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
[
"https://doi.org/10.1021/acs.chemrestox.6b00347"
]
|
| rights |
null
|
| title | Judson_Kleinstreuer_Development and Validation of a Computational Model for Androgen Receptor Activity. |
