Saili_AOP43_Systems Modeling of Developmental Vascular Toxicity
The AOP concept was used to translate ToxCast high-throughput screening data into a ToxPi matrix of 1058 chemicals x 24 features ordered by predicted potential to disrupt angiogenesis.
This dataset is associated with the following publication:
Saili, K., J. Franzosa, N. Baker, R. Ellis-Hutchings, R. Settivari, E. Carney, R. Spencer, T. Zurlinden, N. Kleinstreuer, S. Li, M. Xia, and T. Knudsen. Systems Modeling of Developmental Vascular Toxicity. Current Opinion in Toxicology. Elsevier BV, AMSTERDAM, NETHERLANDS, 15(1): 55-63, (2019).
Complete Metadata
| accessLevel | public |
|---|---|
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Thomas Knudsen",
"hasEmail": "mailto:knudsen.thomas@epa.gov"
}
|
| description | The AOP concept was used to translate ToxCast high-throughput screening data into a ToxPi matrix of 1058 chemicals x 24 features ordered by predicted potential to disrupt angiogenesis. This dataset is associated with the following publication: Saili, K., J. Franzosa, N. Baker, R. Ellis-Hutchings, R. Settivari, E. Carney, R. Spencer, T. Zurlinden, N. Kleinstreuer, S. Li, M. Xia, and T. Knudsen. Systems Modeling of Developmental Vascular Toxicity. Current Opinion in Toxicology. Elsevier BV, AMSTERDAM, NETHERLANDS, 15(1): 55-63, (2019). |
| distribution |
[
{
"title": "https://gaftp.epa.gov/COMPTOX/NCCT_Publication_Data/Saili/jfranzos",
"accessURL": "https://gaftp.epa.gov/COMPTOX/NCCT_Publication_Data/Saili/jfranzos"
}
]
|
| identifier | https://doi.org/10.23719/1503433 |
| keyword |
[
"5HPP-33",
"TNP-470",
"Tox21",
"ToxCast",
"adverse outcome pathway",
"angiogenesis",
"tipping points",
"vEmbryo",
"virtual embryo",
"virtual tissues"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2019-02-27 |
| programCode |
[
"020:095"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
[
"https://doi.org/10.1016/j.cotox.2019.04.004"
]
|
| rights |
null
|
| title | Saili_AOP43_Systems Modeling of Developmental Vascular Toxicity |
