Found 69 datasets matching "Biological pathways".
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Water-borne contaminants were monitored in 69 tributaries of the Laurentian Great Lakes in 2010 and 2014 using semipermeable membrane devices (SPMDs), and polar organic chemical integrative...
Search relevance: 117.24 | Views last month: 0 -
The Maumee River and associated tributaries are an example of a system influenced by a mosaic of contaminant inputs from point and nonpoint sources along a gradient of land uses. To assess the...
Search relevance: 47.53 | Views last month: 0 -
As a case study, chemical occurrence data from a 2012 study in the Great Lakes Basin along with the ToxCast™ effects database were used to calculate exposure-activity ratios (EARs) as a...
Search relevance: 47.27 | Views last month: 0 -
Background Bruton's tyrosine kinase (Btk) is essential for B cell development and function. Mutations of Btk elicit X-linked agammaglobulinemia in humans and X-linked immunodeficiency in...
Search relevance: 41.55 | Views last month: 0 -
Given the limited knowledge of the biological impact of spaceflight, a multi-omics, systems biology approach was used to investigate NASA’s GeneLab data and astronaut biomedical profiles. These...
Search relevance: 40.50 | Views last month: 0 -
Ongoing honey bee colony losses are of significant international concern because of the essential role these insects play in pollinating many high nutrient crops, such as fruits, vegetables, and...
Search relevance: 39.74 | Views last month: 3 -
Supplementary data for "Peter Schumann, Claudia Rivetti, Jade Houghton, Bruno Campos, Geoff Hodges, Carlie LaLone, Combination of computational new approach methodologies for enhancing evidence of...
Search relevance: 39.38 | Views last month: 0 -
Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are used in many consumer applications due to their stain repellency, ability to form water-proof coatings and use in fire suppression. The...
Search relevance: 38.80 | Views last month: 13 -
Prioritization of chemicals was performed on two Areas of Concerns in the Great Lakes An integrated risk surveillance and monitoring approach was applied Bio-effect prediction methodologies were...
Search relevance: 37.83 | Views last month: 1 -
This study's objective was to develop an understanding of the biological effects of space radiation on plants with the goal of producing fresh food during long duration space missions to support...
Search relevance: 37.66 | Views last month: 1 -
Physical forces greatly influence the growth and function of an organism. Altered gravity can perturb normal development and induce corresponding changes in gene expression. Understanding this...
Search relevance: 37.62 | Views last month: 0 -
This study demonstrates the potential of whole-mount in situ hybridization (WISH), in conjunction with quantitative real-time polymerase chain reaction (QPCR) assays, to examine the mechanistic...
Search relevance: 36.48 | Views last month: 0 -
The dataset comprises ten data tables as well as a contents table. Data tables provide information on RT-qPCR primers and assay conditions, significantly altered metabolites, canonical pathways,...
Search relevance: 36.11 | Views last month: 0 -
Exotic annual grasses [EAG] are one of the most damaging biological stressors in western North America. Despite numerous environmental and societal impacts associated with EAG there remains a need...
Search relevance: 35.87 | Views last month: 0 -
The U.S. Tox21 Federal collaboration, which currently quantifies the biological effects of nearly 10,000 chemicals via quantitative high-throughput screening(qHTS) in in vitro model systems, is...
Search relevance: 34.45 | Views last month: 0 -
Background: The radiation bystander response is an important component of the overall response of cells to radiation and critical to understanding health risks of radiation exposure to humans. The...
Search relevance: 34.22 | Views last month: 0 -
Background/Objectives: The waterflea Daphnia is an interesting candidate for bioregenerative life support systems (BLSS). These animals are particularly promising because of their central role in...
Search relevance: 32.69 | Views last month: 0 -
Background/Objectives: The waterflea Daphnia is an interesting candidate for bioregenerative life support systems (BLSS). These animals are particularly promising because of their central role in...
Search relevance: 32.68 | Views last month: 0 -
We examined whether contaminants present in surface waters could be prioritized for further assessment by linking the presence of specific chemicals to gene expression changes in exposed fish....
Search relevance: 31.55 | Views last month: 0 -
The eastern oyster (Crassostrea virginica) supports a large aquaculture industry and is a keystone species along the Atlantic seaboard. Native oysters are routinely exposed to a complex mixture of...
Search relevance: 30.14 | Views last month: 2
