• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Some provocative thoughts on damage and repair of DNA

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• Organization: U.S. Environmental Protection Agency
• Updated: 2017-12-21

Datasets used in ORD-025118: Using a Gene Expression Biomarker to Identify DNA Damage-Inducing Agents in Microarray Profiles. This dataset is associated with the following publication: Corton,...

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• Organization: U.S. Environmental Protection Agency
• Updated: 2018-05-15

The dataset shows the results of the Running Fisher test between the TGx-DDI biomarker and each of the qPCR-generated gene lists from chemical treatments in TK6 cells. The results are divided into...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background The issue remains unresolved as to whether low frequency magnetic fields can affect cell behaviour, with the possibility that they may be in part responsible for the increased...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background: Uracil DNA glycosylases (UDGs) are major repair enzymes that protect DNA from mutational damage caused by uracil incorporated as a result of a polymerase error or deamination...

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• Organization: Department of the Interior
• Updated: 2023-08-14T00:00:00Z

This dataset provides results for the following: (1) metals concentrations in soils surrounding breeding song bird nest sites; (2) metals concentrations in invertebrates (earthworm and grub...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

To understand gene expression responses in confluent human fibroblast in microgravity conditions to bleomycin treatment. Confluent human fibroblasts AG01522 were flown to the International Space...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background The p53 protein is activated by genotoxic stress, oncogene expression and during senescence, p53 transcriptionally activates genes involved in growth arrest and apoptosis. p53...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

Whole seedlings of wild type (4d) and atm mutants (4d) have been analyzed after a gamma ray irradiation of 0.75h 1.5h 3h & 5h (time course). Roots of wt (4d) atm (3d) and atr (4d) mutants have...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background It has become increasingly clear that β-cell failure plays a critical role in the pathogenesis of type 2 diabetes. Free-radical mediated β-cell damage has been intensively...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still controversial. A mRNA microarray and...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still controversial. A mRNA microarray and...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

RAD51 a multifunctional protein plays a central role in DNA replication and homologous recombination repair and is known to be involved in cancer development. We identified a novel role for RAD51...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

RAD51 a multifunctional protein plays a central role in DNA replication and homologous recombination repair and is known to be involved in cancer development. We identified a novel role for RAD51...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still controversial. A mRNA microarray and...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still controversial. A mRNA microarray and...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still controversial. A mRNA microarray and...

• html

• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still controversial. A mRNA microarray and...

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• Organization: Department of the Interior
• Updated: 2020-08-27T00:00:00Z

- Observations of test subjects and hatching data - Body weight, organ/tissue weights - Biomarker data (oxidative stress indicators, oxidative DNA damage, thyroid hormones, histological...

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• Organization: Department of the Interior
• Updated: 2020-09-22T00:00:00Z

- Observations of test subjects and hatching data - Body weight, organ/tissue weights - Biomarker data (oxidative stress indicators, oxidative DNA damage, thyroid hormones, histological findings)...

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