• Organization: U.S. Environmental Protection Agency
• Updated: 2021-09-23

Gene expression data on >20 year-old, paired frozen and archival FFPE liver samples generated using targeted resequencing (TempO-Seq) and whole-genome RNA-sequencing methods. Samples were...

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• Organization: U.S. Environmental Protection Agency
• Updated: 2016-12-01

se of archival resources has been limited to date by inconsistent methods for genomic profiling of degraded RNA from formalin-fixed paraffin-embedded (FFPE) samples. RNA-seq offers a novel way to...

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• Organization: U.S. Environmental Protection Agency
• Updated: 2017-09-11

Low RNA yield and quality limit use of formalin-fixed paraffin-embedded (FFPE) tissue samples for genomic analyses. In this study, we evaluated methods to demodify RNA highly fragmented and...

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• Organization: U.S. Environmental Protection Agency
• Updated: 2021-02-17

The primary goal of this study was to investigate the effects of whether organocatalyst (ORGΔ) treatment improves DNA-sequencing data by overcoming formalin-induced artifacts from clinical...

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• Organization: Department of the Interior
• Updated: 2020-09-25T00:00:00Z

There is an increasing emphasis on effects-based monitoring to document responses associated with exposure to complex mixtures of chemicals, climate change, pathogens, parasites and other...

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