Found 8 datasets matching "MHC Class II".
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Most techniques that identify antigen-specific T cells are dependent on the response of these cells to the relevant antigen in culture. Soluble multimers of MHC molecules, when occupied with the...
Search relevance: 195.17 | Views last month: 0 -
Human leucocyte antigen (HLA) class II molecules have been shown to be associated with predisposition to rheumatoid arthritis (RA). We generated HLA-DR and DQ transgenic mice that lacked...
Search relevance: 98.83 | Views last month: 0 -
There is provided a tolerogenic human peptide, capable of binding to an MHC class I or II molecule without further antigen processing, for use in the treatment and/or prevention of multiple...
Search relevance: 72.79 | Views last month: 0 -
Inherited susceptibility to rheumatoid arthritis (RA) is associated with the DRB1 genes encoding the human leukocyte antigen (HLA)-DR4 and HLA-DR1 molecules. Transgenic mice expressing these...
Search relevance: 71.12 | Views last month: 0 -
A method of preparing a modified granulocyte colony stimulating factor (G-CSF) protein having reduced immunogenicity relative to human G-CSF comprises the steps of (i) identifying one or more...
Search relevance: 61.29 | Views last month: 0 -
Recent advances suggest that toll-like receptors, various cytokines, cicosanoids, free radicals and macrophage migration inhibitory factor (MIF) play an important role in the pathobiology of...
Search relevance: 59.59 | Views last month: 3 -
Excel files containing raw data used to generate figures throughout manuscript. This dataset is associated with the following publication: Dean , T., D. Betancourt , J. Kim, L. Harvey, A. Evans,...
Search relevance: 56.87 | Views last month: 0 -
Background Experimental colitis with features similar to inflammatory bowel disease (IBD) has initially been described. A detailed analysis of inflammatory cells has not yet been...
Search relevance: 44.96 | Views last month: 0
