Found 12 datasets matching "PBPK models".
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Source Code for the manuscript "Characterizing Variability and Uncertainty for Parameter Subset Selection in PBPK Models" -- This R code generates the results presented in this manuscript; the...
Search relevance: 161.93 | Views last month: 3 -
The dataset includes source code that was used to perform analyses described in the manuscript "Evaluating Impact of Anatomical and Physiological Variability on Human Equivalent Doses Using PBPK...
Search relevance: 143.28 | Views last month: 0 -
How to access data for "Decrane R, Stoker T, Murr A, Ford J, El-Masri H. Cross species extrapolation of the disruption of thyroid hormone synthesis by oxyfluorfen using in vitro data,...
Search relevance: 129.25 | Views last month: 1 -
The data set includes source code that implements a PBPK model template that has been extended with features capable of implementing models for volatile organic compounds (VOCs). It also includes...
Search relevance: 72.10 | Views last month: 3 -
The data set includes source code that implements a PBPK template model applicable to PFAS. It includes data digitized from Kim et al. (2018), Kim et al. (2019), and Loccisano et al. (2012) used...
Search relevance: 68.89 | Views last month: 12 -
The data set includes source code for a "PBPK model template" that can be used to implement physiologically based pharmacokinetic (PBPK) models with various different structural designs and...
Search relevance: 66.81 | Views last month: 1 -
Generic physiologically-based pharmacokinetic (PBPK) models were used to explore how saturable absorption or clearance can influence the shape of the internal to external concentration (IEC)...
Search relevance: 65.77 | Views last month: 1 -
MCSimMod is a flexible and efficient R package that can be used for implementation and application of physiologically based pharmacokinetic (PBPK) and other ordinary differential equation (ODE) models.
Search relevance: 64.46 | Views last month: 0 -
Background The application of physiologically based pharmacokinetic models (PBPK) to human studies has been limited by the lack of the detailed organ information that is required for...
Search relevance: 62.27 | Views last month: 0 -
Contains values from pbpk models for each study on n-butanol effects. This dataset is associated with the following publication: Segal, D., A. Bale, L. Phillips, A. Sasso, P. Schlosser, C....
Search relevance: 56.57 | Views last month: 0 -
This repository contains scripts, input files, and some example output files for the Residential Population Generator, an R-based tool to generate synthetic human residental populations to use in...
Search relevance: 49.23 | Views last month: 1 -
Perchlorate is an environmental contaminant that interferes with iodine uptake via the NIS transporter into the thyroid gland, reducing thyroid hormone (TH) synthesis. As adequate supplies of TH...
Search relevance: 32.05 | Views last month: 1
