Found 29 datasets matching "Predictive Toxicology".
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ToxRefDB comprises information from over fifty years of in vivo toxicity data. The database includes information for over 1000 chemicals, and is being used as a primary source of data for...
Search relevance: 165.62 | Views last month: 7 -
Chemical structures, RMSD values, docking scores, additional tables and figures, and methodological details (PDF) Additional information concerning the starting data set, EPA-ARDB.csv...
Search relevance: 152.25 | Views last month: 0 -
A publised mansucript describing a quantitative adverse outcome pathway (qAOP) and its relevance to risk assessment. This dataset is not publicly accessible because: This work describes...
Search relevance: 104.42 | Views last month: 0 -
The systems map described in this manuscript for neurulation will set the stage for constructing mathematical models and computer simulation of neural tube closure for human-relevant AOPs and...
Search relevance: 97.77 | Views last month: 0 -
The data presented here support the application of the Stemina devTOXqP platform for predictive toxicology and further demonstrate its value in ToxCast as a novel resource that can generate...
Search relevance: 90.54 | Views last month: 0 -
Proportional response addition (Prop-RA), a model for predicting response from chemical mixture exposure, is demonstrated, and evaluated by statistically evaluating data on all possible binary...
Search relevance: 76.08 | Views last month: 1 -
This dataset includes data used to generate Figures 4C, 5B, 5C, and 5D in Tal et al. Screening for angiogenic inhibitors in zebrafish to evaluate a predictive model for developmental vascular...
Search relevance: 56.39 | Views last month: 0 -
Supplemental data for "LaLone CA, Blatz DJ, Jensen MA, Vliet SMF, Mayasich S, Mattingly KZ, Transue TR, Melendez W, Wilkinson A, Simmons CW, Ng C, Zhang C, Zhang Y. From Protein Sequence to...
Search relevance: 55.04 | Views last month: 0 -
The U.S. Tox21 Federal collaboration, which currently quantifies the biological effects of nearly 10,000 chemicals via quantitative high-throughput screening(qHTS) in in vitro model systems, is...
Search relevance: 53.64 | Views last month: 0 -
Dataset for Baker, et al., Identifying candidate reference chemicals for in vitro testing of the retinoid pathway for predictive developmental toxicity, published in journal Altex,...
Search relevance: 51.97 | Views last month: 0 -
The Distributed Structure Searchable Toxicity (DSSTox) online resource provides high quality chemical structures and annotations in association with toxicity data. It helps to build a data...
Search relevance: 49.78 | Views last month: 1 -
Microarray experiments used in the study. This dataset is associated with the following publication: Corton, J., K. Korunes, J. Abedini, H. El-Masri, J. Brown, K. Friedman, Y. Liu, C. Martini,...
Search relevance: 49.37 | Views last month: 0 -
Dataset used to determine the predictive accuracy of the HDACi biomarker. This dataset is associated with the following publication: Cho, E., A. Rowan-Carroll, A. Williams, C. Corton, H. Li, A....
Search relevance: 48.91 | Views last month: 1 -
Supporting Information for "Jensen, M.A., Blatz, D.J. and LaLone, C.A. (2023), Defining the Biologically Plausible Taxonomic Domain of Applicability of an Adverse Outcome Pathway: A Case Study...
Search relevance: 48.33 | Views last month: 0 -
Dataset used in ORD-040059: Identification of Chemical Modulators of NF-κB Using a Gene Expression Biomarker Approach that includes publicaly available microarray datasets. This dataset is...
Search relevance: 47.95 | Views last month: 1 -
To determine the best way to select predictive groups of genes, we used published microarray data from dose-response studies on six chemicals in rats exposed orally for 5, 14, 28, and 90 days. We...
Search relevance: 46.54 | Views last month: 0 -
Morphogenetic events are driven by cell-generated physical forces and complex cellular dynamics. To improve our capacity to predict developmental effects from cellular alterations, we built a...
Search relevance: 44.52 | Views last month: 0 -
thyroid hormones in serum and in brain were measured in fetal and neonatal rat cortex after graded levels of a thyroid hormone synthesis inhibitor were administered to pregnant rat dams. A number...
Search relevance: 44.22 | Views last month: 0 -
The original contributions presented in the study are included in the article and online through the TAME Toolkit, available at: https://uncsrp.github.io/Data-Analysis-Training-Modules/, with...
Search relevance: 43.54 | Views last month: 3 -
Data and supplemental files from COMPARA (A large-scale modeling project). COMPARA combined multiple models developed in collaboration with modelers and computational toxicology scientists from 25...
Search relevance: 41.45 | Views last month: 0
