Found 6 datasets matching "actin-filaments".
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Background The tropomodulins (TMODs) are a family of proteins that cap the pointed ends of actin filaments. Four TMODs have been identified in humans, with orthologs in mice. Mutations...
Search relevance: 124.82 | Views last month: 1 -
Background Liver sinusoidal endothelial cells (LSECs) react to different anti-actin agents by increasing their number of fenestrae. A new structure related to fenestrae formation could...
Search relevance: 73.13 | Views last month: 0 -
Background The cell surface undergoes continuous change during cell movement. This is characterized by transient protrusion and partial or complete retraction of microspikes, filopodia,...
Search relevance: 71.31 | Views last month: 2 -
Background Capping protein (CP), a heterodimer of α and β subunits, is found in all eukaryotes. CP binds to the barbed ends of actin filaments in vitro and controls actin assembly and...
Search relevance: 71.23 | Views last month: 0 -
Background Three types of molecular motors play an important role in the organization, dynamics and transport processes associated with the cytoskeleton. The myosin family of molecular...
Search relevance: 65.36 | Views last month: 1 -
Background NF1 refers to type 1 neurofibromatosis syndrome, which has been linked with mutations of the large NF1 gene. NF1 tumor suppressor protein, neurofibromin, has been shown to...
Search relevance: 55.92 | Views last month: 0