Found 11 datasets matching "acute-leukemia".
-
Background The timed-sequential chemotherapy regimen consisting of etoposide, mitoxantrone and cytarabine (EMA) is an effective therapy for relapsed or refractory acute myelogenous...
Search relevance: 171.69 | Views last month: 0 -
Certain mouse strains such as CBA C3H and RFM have high incidence of radiation-induced acute myeloid leukemia (AML). The data in this series wer generated by using spleen DNA from CBA mice which...
Search relevance: 161.95 | Views last month: 0 -
Certain mouse strains such as CBA C3H and RFM have high incidence of radiation-induced acute myeloid leukemia (AML). The data in this series wer generated by using spleen DNA from CBA mice which...
Search relevance: 161.62 | Views last month: 0 -
Background Circulating levels of tumor necrosis factor (TNF) and lymphotoxin-α (LT-α) have been associated with outcome in solid and hematologic malignancies. Within the TNF gene and the...
Search relevance: 107.53 | Views last month: 0 -
Idhifa (enasidenib mesylate) is a prescription oral tablet that inhibits the IDH2 enzyme, used to treat adults with relapsed or refractory acute myeloid leukemia (AML) who have an IDH2 mutation....
Search relevance: 69.42 | Views last month: 0 -
Decitabine is an intravenous prescription drug used to treat certain blood disorders like myelodysplastic syndromes and acute myeloid leukemia. It comes as a lyophilized powder in 50 mg vials,...
Search relevance: 66.75 | Views last month: 0 -
Besponsa (inotuzumab ozogamicin) is an intravenous prescription drug, supplied as a lyophilized powder for injection. It's an immunoconjugate that targets CD22 on cancer cells, leading to DNA...
Search relevance: 66.16 | Views last month: 0 -
Clofarabine is an intravenous injection used to treat relapsed or refractory acute lymphoblastic leukemia, particularly in pediatric patients. It belongs to the class of nucleoside metabolic...
Search relevance: 65.95 | Views last month: 0 -
Background We propose two different formulations of the Rasch statistical models to the problem of relating gene expression profiles to the phenotypes. One formulation allows us to...
Search relevance: 55.57 | Views last month: 0 -
Background The NUP98 gene is involved in multiple rearrangements in haematological malignancy. The leukemic cells in an acute myeloid leukemia (AML) patient with a t(9;11)(p22;p15) were...
Search relevance: 49.98 | Views last month: 0 -
IL-6 is a multifunctional cytokine produced by lymphoid and nonlymphoid cells; it regulates immune responses, acute-phase reactions, and inflammation. IL-6 signaling is mediated exclusively by the...
Search relevance: 44.67 | Views last month: 0
