Found 21 datasets matching "airway-inflammation".
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Chronic airway inflammation is one of the main features of asthma. Release of mediators from infiltrating inflammatory cells in the airway mucosa has been proposed to contribute directly or...
Search relevance: 276.63 | Views last month: 0 -
Asthma was originally described as an inflammatory disease that predominantly involves the central airways. Pathological and physiological evidence reported during the past few years suggests that...
Search relevance: 263.63 | Views last month: 0 -
There is increasing evidence for a close link between the upper and the lower respiratory tracts and the fact that rhinitis has an important impact on asthma. Several clinical and experimental...
Search relevance: 173.79 | Views last month: 0 -
Allergic bronchial asthma (BA) is characterized by chronic airway inflammation, development of airway hyperreactivity and recurrent reversible airway obstruction. T-helper 2 cells and their...
Search relevance: 134.76 | Views last month: 1 -
Pulmonary surfactant is a unique mixture of lipids and surfactant-specific proteins that covers the entire alveolar surface of the lungs. Surfactant is not restricted to the alveolar compartment;...
Search relevance: 128.32 | Views last month: 1 -
Interleukin-5 is produced by a number of cell types, and is responsible for the maturation and release of eosinophils in the bone marrow. In humans, interleukin-5 is a very selective cytokine as a...
Search relevance: 72.91 | Views last month: 0 -
Employing acrolein, a potent airway irritant, and TCE, with low irritancy, authors hypothesized that airway injury and inflammation would be involved in eliciting neuroendocrine-mediated systemic...
Search relevance: 69.51 | Views last month: 0 -
This dataset provides information on how differences in chemical composition of PM across seasons contribute to different biological effects and modify antiviral host defense response in airway...
Search relevance: 65.65 | Views last month: 0 -
One component of host defense at mucosal surfaces seems to be epithelium-derived antimicrobial peptides. Antimicrobial peptides are classified on the basis of their structure and amino acid...
Search relevance: 65.12 | Views last month: 0 -
Since their discovery 15 years ago, the role of γδ T cells has remained somewhat elusive. Responses of γδ T cells have been found in numerous infectious and non-infectious diseases. New evidence...
Search relevance: 64.58 | Views last month: 0 -
Many pulmonary diseases preferentially affect the large airways or the alveoli. Although the mechanisms are often particular to each disease process, site-specific differences in leukocyte...
Search relevance: 61.47 | Views last month: 0 -
The 97th American Thoracic Society meeting proved to be an excellent meeting, providing a wealth of new information on inflammatory diseases of the airways. Once again there appeared to be an...
Search relevance: 59.19 | Views last month: 0 -
Background Inhalation of Ascaris suum antigen by allergic monkeys causes an immediate bronchoconstriction and delayed allergic reaction, including a pulmonary inflammatory infiltrate. To...
Search relevance: 56.90 | Views last month: 0 -
Airway hyper-reactivity is a characteristic feature of many inflammatory lung diseases and is defined as an exaggerated degree of airway narrowing. Chemokines and their receptors are involved in...
Search relevance: 56.53 | Views last month: 0 -
Background Respiratory syncytial virus (RSV) infection of airway epithelial cells stimulates the expression and secretion of a variety of cytokines including the chemotactic cytokines...
Search relevance: 54.81 | Views last month: 0 -
This study sought to examine whether mild preexisting allergic airways disease enhances the response of the lungs to burn pit smoke emissions. The findings indicate that exposure to house dust...
Search relevance: 53.12 | Views last month: 1 -
Background: Recent investigations have shown that leukocyte activation is involved in the pathogenesis of ventilator-associated lung injury. This study was designed to investigate...
Search relevance: 50.39 | Views last month: 0 -
Background Evidence suggests that both the migration and activation of neutrophils into the airway is of importance in pathological conditions such as pulmonary emphysema. In the present...
Search relevance: 50.24 | Views last month: 0 -
Background In asthma and other allergic disorders, the activation of mast cells by IgE and antigen induces the cells to release histamine and other mediators of inflammation, as well as...
Search relevance: 41.81 | Views last month: 0 -
Objective: Inhalation of ozone activates central sympathetic-adrenal-medullary and hypothalamic-pituitary-adrenal stress axes. While airway neural networks are known to communicate noxious stimuli...
Search relevance: 41.55 | Views last month: 1
