Found 13 datasets matching "alternative-splicing".
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Background Thioredoxin reductase (TR) is a redox active protein involved in many cellular processes as part of the thioredoxin system. Presently there are three recognised forms of...
Search relevance: 225.04 | Views last month: 0 -
Background Receptor protein tyrosine phosphatase rho (RPTPρ, gene symbol PTPRT) is a member of the type IIB RPTP family. These transmembrane molecules have been linked to signal...
Search relevance: 172.25 | Views last month: 0 -
We sought to comprehensively elucidate the transcriptomic underpinnings of microgravity-induced muscle phenotypes in mice by evaluating both differential gene expression (DGE) and changes in...
Search relevance: 156.41 | Views last month: 0 -
Background The tropomodulins (TMODs) are a family of proteins that cap the pointed ends of actin filaments. Four TMODs have been identified in humans, with orthologs in mice. Mutations...
Search relevance: 64.40 | Views last month: 1 -
Background: Germ-cell nuclear factor (GCNF, NR6AI) is an orphan nuclear receptor. Its expression pattern suggests it functions during embryogenesis, in the placenta and in germ-cell...
Search relevance: 62.48 | Views last month: 0 -
Background The ubiquitin-dependent protein degradation pathway is essential for the proteolysis of intracellular proteins and peptides. Deubiquitinating enzymes constitute a complex...
Search relevance: 58.20 | Views last month: 0 -
Background Since contradictory results have been reported, we reanalysed the 77C→G transition in exon 4 of the protein-tyrosine phosphatase receptor-type C (PTPRC also known as CD45) in...
Search relevance: 54.69 | Views last month: 0 -
Background Alternative mRNA splicing of αi2, a heterotrimeric G protein α subunit, has been shown to produce an additional protein, termed sαi2. In the sαi2 splice variant, 35 novel...
Search relevance: 48.04 | Views last month: 0 -
Background Annotation of eukaryotic genomes is a complex endeavor that requires the integration of evidence from multiple, often contradictory, sources. With the ever-increasing amount...
Search relevance: 47.04 | Views last month: 0 -
Background: Sodium bicarbonate cotransporter (NBC) genes encode proteins that execute coupled Na+ and HCO3- transport across epithelial cell membranes. We report the discovery,...
Search relevance: 46.03 | Views last month: 0 -
Background Mucolipidosis type IV (MLIV) is an autosomal recessive lysosomal storage disorder characterized by severe neurologic and ophthalmologic abnormalities. Recently the MLIV gene,...
Search relevance: 45.33 | Views last month: 1 -
This multi-reserve project led by the ACE Basin Reserve convened a series of workshops to provide guidance and assistance on siting, construction, installation, and interpretation of Motus sites...
Search relevance: 38.02 | Views last month: 0 -
The Coachella paleoseismic site is located on the San Andreas Fault along the northeast edge of the Coachella Valley in southern California, southwest of the intersection of Dillon Road and Avenue...
Search relevance: 34.67 | Views last month: 0
