Found 62 datasets matching "anti-inflammatory".
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Background Crocus sativus L. (saffron) is used in folk medicine, for example as an antiedematogenic agent. We aimed to evaluate the antinociceptive and anti-inflammatory activity of...
Search relevance: 257.83 | Views last month: 2 -
Large scale clinical trials demonstrate significant reductions in cardiovascular event rates with statin therapy. The observed benefit of statin therapy, however, may be larger in these trials...
Search relevance: 237.74 | Views last month: 1 -
The importance of balanced pro-inflammatory and anti-inflammatory mechanisms in diffuse lung disease
The lung responds to a variety of insults in a remarkably consistent fashion but with inconsistent outcomes that vary from complete resolution and return to normal to the destruction of normal...
Search relevance: 192.91 | Views last month: 1 -
Most anti-inflammatory drugs have been associated with an increased risk of serious upper gastrointestinal complications. Epidemiological studies have estimated the magnitude of the risk for...
Search relevance: 169.50 | Views last month: 0 -
Nonsteroidal anti-inflammatory drugs (NSAIDs) belong to the most frequently used drugs. The discovery of an inducible isoform of cyclo-oxygenase (COX-2) has led to an intensive worldwide search...
Search relevance: 157.81 | Views last month: 0 -
Despite the recent introduction of biological response modifiers and potent new small-molecule antirheumatic drugs, the efficacy of methotrexate is nearly unsurpassed in the treatment of...
Search relevance: 142.83 | Views last month: 5 -
Although early antibiotic treatment of patients with septic arthritis eradicates bacteria, joint destruction commonly results from the unregulated host inflammatory responses to infection. The...
Search relevance: 121.30 | Views last month: 0 -
Background Peperomia pellucida is popularly known as coraçãozinho in the Brazilian northeast and is used in the treatment of abscesses, furuncles, and conjunctivitis. Our work aimed to...
Search relevance: 112.73 | Views last month: 0 -
Glucocorticoids (GCs) are routinely used as anti-inflammatory drugs in the treatment of asthma. They act through binding to glucocorticoid receptor α (GRα), which represses numerous genes encoding...
Search relevance: 108.54 | Views last month: 0 -
Background Tabebuia avellanedae is a tree from the Bignoniaceae family. Commonly know as "pau d'arco" in Brazil, its inner bark is used as analgesic, anti-inflammatory, antineoplasic and...
Search relevance: 96.78 | Views last month: 0 -
A cosmetic or dermatological composition contains by weight (a) a red light-filtering colorant (0.01-5%); and (b) an antiinflammatory agent (0.0001-10%). ACTIVITY : Dermatological;...
Search relevance: 84.71 | Views last month: 1 -
Inflammatory diseases of the respiratory tract are commonly associated with elevated production of nitric oxide (NO•) and increased indices of NO• -dependent oxidative stress. Although NO• is...
Search relevance: 78.74 | Views last month: 1 -
Blends of quercetin and isoflavones from the group consisting of genestein, daidzein and glycetin display synergistic effects when applied as anti-inflammatory agent or as skin agent in particular...
Search relevance: 76.24 | Views last month: 0 -
Human tumour necrosis factor (TNF)-like weak inducer of apoptosis (hTWEAK) and two anti-hTWEAK mAbs were tested for their ability to elicit or block inflammatory responses in cultured human dermal...
Search relevance: 74.80 | Views last month: 1 -
It is not known to what extent glucocorticoid hormones cause their anti-inflammatory actions and their undesirable side effects by the same or different molecular mechanisms. Glucocorticoids...
Search relevance: 72.12 | Views last month: 0 -
The 97th American Thoracic Society meeting proved to be an excellent meeting, providing a wealth of new information on inflammatory diseases of the airways. Once again there appeared to be an...
Search relevance: 69.40 | Views last month: 0 -
There is mounting evidence for a role of the growth factor granulocyte-macrophage colony-stimulating factor (GM-CSF) in inflammatory disease, including arthritis. In the present study, we examined...
Search relevance: 65.53 | Views last month: 0 -
The cytokine tumour necrosis factor (TNF)α is a vital mediator of the innate immune response, and a pleiotropic regulator of cellular function. Its involvement in rheumatoid arthritis is...
Search relevance: 65.42 | Views last month: 0 -
Indomethacin is a prescription nonsteroidal anti-inflammatory drug (NSAID) available as 75 mg extended-release oral capsules. It works by inhibiting cyclooxygenase enzymes to reduce pain,...
Search relevance: 64.83 | Views last month: 0 -
Background Food allergies are generally associated with gastrointestinal upset, but in many patients systemic reactions occur. However, the systemic effects of food allergies are poorly...
Search relevance: 64.19 | Views last month: 2