Found 19 datasets matching "anti-inflammatory-effects".
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Background Crocus sativus L. (saffron) is used in folk medicine, for example as an antiedematogenic agent. We aimed to evaluate the antinociceptive and anti-inflammatory activity of...
Search relevance: 256.22 | Views last month: 2 -
Despite the recent introduction of biological response modifiers and potent new small-molecule antirheumatic drugs, the efficacy of methotrexate is nearly unsurpassed in the treatment of...
Search relevance: 183.77 | Views last month: 5 -
Blends of quercetin and isoflavones from the group consisting of genestein, daidzein and glycetin display synergistic effects when applied as anti-inflammatory agent or as skin agent in particular...
Search relevance: 97.49 | Views last month: 0 -
It is not known to what extent glucocorticoid hormones cause their anti-inflammatory actions and their undesirable side effects by the same or different molecular mechanisms. Glucocorticoids...
Search relevance: 92.34 | Views last month: 0 -
Human tumour necrosis factor (TNF)-like weak inducer of apoptosis (hTWEAK) and two anti-hTWEAK mAbs were tested for their ability to elicit or block inflammatory responses in cultured human dermal...
Search relevance: 87.89 | Views last month: 1 -
Although early antibiotic treatment of patients with septic arthritis eradicates bacteria, joint destruction commonly results from the unregulated host inflammatory responses to infection. The...
Search relevance: 82.66 | Views last month: 0 -
Nonsteroidal anti-inflammatory drugs (NSAIDs) belong to the most frequently used drugs. The discovery of an inducible isoform of cyclo-oxygenase (COX-2) has led to an intensive worldwide search...
Search relevance: 80.77 | Views last month: 0 -
Inflammatory cytokines may negatively influence contractility and contribute to the remodelling process in the failing myocardium. Traditional cardiovascular drugs appear to have little influence...
Search relevance: 78.91 | Views last month: 0 -
Statins reduce mortality of patients with coronary artery disease (CAD). However, by protocol, trials have excluded patients with chronic heart failure. Since the prevalent etiology of heart...
Search relevance: 78.36 | Views last month: 2 -
Background Crude extracts of Chelidonium majus, and also purified compounds derived from crude extracts of this plant, have been reported to exhibit anti-viral, anti-inflammatory,...
Search relevance: 76.18 | Views last month: 0 -
Background Food allergies are generally associated with gastrointestinal upset, but in many patients systemic reactions occur. However, the systemic effects of food allergies are poorly...
Search relevance: 75.97 | Views last month: 2 -
Background Inflammatory reactions occurring in the brain after ischemia may contribute to secondary damage. In the present study, effects of minocycline, an anti-inflammatory agent,...
Search relevance: 75.02 | Views last month: 0 -
The invention is a topical, anti-inflammatory medical, cosmetic, or dermatological preparation comprising at least one compound of the formula (DKH) wherein n is 1 or 2; and R1 and R2,...
Search relevance: 74.48 | Views last month: 0 -
Background Sulfasalazine is a widely used anti-inflammatory agent in the treatment of inflammatory bowel disease and several rheumatological disorders. Although as many as 20% of treated...
Search relevance: 70.71 | Views last month: 2 -
Large scale clinical trials demonstrate significant reductions in cardiovascular event rates with statin therapy. The observed benefit of statin therapy, however, may be larger in these trials...
Search relevance: 70.60 | Views last month: 1 -
One component of host defense at mucosal surfaces seems to be epithelium-derived antimicrobial peptides. Antimicrobial peptides are classified on the basis of their structure and amino acid...
Search relevance: 66.72 | Views last month: 0 -
The transcription factors nuclear factor interleukin-6 (NF-IL6), early growth response-1 (EGR-1) and hypoxia-inducible factor-1 (HIF-1) have important roles in the molecular pathophysiology of...
Search relevance: 65.07 | Views last month: 0 -
Background Tabebuia avellanedae is a tree from the Bignoniaceae family. Commonly know as "pau d'arco" in Brazil, its inner bark is used as analgesic, anti-inflammatory, antineoplasic and...
Search relevance: 58.24 | Views last month: 0 -
Background It has been suggested that one aspect of non-steroidal anti-inflammatory drugs induced intestinal damage is due to either uncoupling of mitochondrial oxidative phosphorylation...
Search relevance: 52.60 | Views last month: 0
