Found 31 datasets matching "autoimmune-disease".
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Background An increased prevalence of coeliac disease in patients with primary biliary cirrhosis has been recently reported. However, in other studies the association has not been...
Search relevance: 213.22 | Views last month: 2 -
Proteomics technologies enable profiling of autoantibody responses using biological fluids derived from patients with autoimmune disease. They provide a powerful tool to characterize autoreactive...
Search relevance: 175.63 | Views last month: 11 -
Immune ablation and stem-cell therapy in autoimmune disease: Introduction
Search relevance: 171.31 | Views last month: 0 -
In the past 5 years, around 350 patients have received haematopoietic stem cell (HSC) transplantation for an autoimmune disease, with 275 of these registered in an international data base in Basel...
Search relevance: 148.34 | Views last month: 2 -
Treatment of rats suffering from florid chronic progressive systemic arthritis or from chronic remitting/relapsing encephalomyelitis with autologous bone marrow transplantation (BMT) is highly...
Search relevance: 141.33 | Views last month: 0 -
Studies on immunological reconstitution after immune ablation and stem-cell therapy may yield important clues to our understanding of the pathogenesis of human autoimmune disease, due to the...
Search relevance: 132.18 | Views last month: 1 -
Systemic lupus erythematosus is the prototype multisystem autoimmune disease. A strong genetic component of susceptibility to the disease is well established. Studies of murine models of systemic...
Search relevance: 112.29 | Views last month: 7 -
Relapsing polychondritis is an autoimmune disease in which an inappropriate immune response destroys cartilage. Cartilage of the ears, larynx and nose rather than spine and joint cartilage is...
Search relevance: 108.58 | Views last month: 0 -
Background The autoimmune destruction of exocrine glands that defines primary Sjögren's syndrome (1°SS) often extends to non-exocrine organs including the liver. We aimed to determine...
Search relevance: 106.12 | Views last month: 1 -
Background The autoimmune thyroid diseases (AITDs), comprising Graves' disease (GD) and Hashimoto's thyroiditis (HT), appear to develop as a result of complex interactions between...
Search relevance: 105.87 | Views last month: 2 -
Results and new hypotheses in animal models often stimulate development of new paradigms in how we view rheumatoid arthritis (RA). The complexity of RA does, however, eventually lead to the...
Search relevance: 104.49 | Views last month: 0 -
The Sa system is a recently described immune system that has a specificity and positive predictive value of nearly 100% for rheumatoid arthritis (RA) in Asia, Europe and the Americas. Its...
Search relevance: 104.33 | Views last month: 0 -
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the production of autoantibodies to a wide range of self-antigens. Recent genome screens have implicated...
Search relevance: 92.99 | Views last month: 0 -
Background The autoimmune thyroid diseases (AITDs), such as Graves' disease (GD) and Hashimoto's thyroiditis (HT), appear to develop as a result of complex interactions between...
Search relevance: 86.02 | Views last month: 0 -
The present disclosure concerns the treatment of a patient with autoimmune disease, including AIDS, by neutralizing, removing or inhibiting different types of interferons, tumor necrosis factor,...
Search relevance: 69.47 | Views last month: 0 -
The diagnosis of rheumatoid arthritis (RA) is primarily based on clinical symptoms, so it is often difficult to diagnose RA in very early stages of the disease. A disease-specific autoantibody...
Search relevance: 60.23 | Views last month: 1 -
Autoimmune diseases that are resistant to conventional treatment cause severe morbidity and even mortality. In the present study we demonstrate that complete remissions can be achieved in...
Search relevance: 57.10 | Views last month: 0 -
The present invention relates to a method for treating autoimmune diseases, more particularly selected from the group consisting of multiple sclerosis, ulcerative colitis, Chron's disease,...
Search relevance: 55.24 | Views last month: 3 -
The induction of autoantibodies to U1 small nuclear ribonucleoprotein (U1 snRNP) complexes is not well understood. We present evidence that healthy individuals with cytomegalovirus (CMV) infection...
Search relevance: 55.24 | Views last month: 0 -
AMJEVITA (adalimumab-atto) is a biosimilar medication to Humira, containing the active ingredient adalimumab, a monoclonal antibody that blocks tumor necrosis factor (TNF) to reduce inflammation....
Search relevance: 54.73 | Views last month: 0