Found 27 datasets matching "autoimmune-diseases".
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The role of autoantibodies in the etiology of autoimmune diseases remains unclear. However, an examination of the sequences of these autoantibodies can be informative. Antibody sequences that...
Search relevance: 226.35 | Views last month: 0 -
Autoimmune diseases that are resistant to conventional treatment cause severe morbidity and even mortality. In the present study we demonstrate that complete remissions can be achieved in...
Search relevance: 208.62 | Views last month: 0 -
Background The autoimmune thyroid diseases (AITDs), comprising Graves' disease (GD) and Hashimoto's thyroiditis (HT), appear to develop as a result of complex interactions between...
Search relevance: 167.73 | Views last month: 2 -
The present invention relates to a method for treating autoimmune diseases, more particularly selected from the group consisting of multiple sclerosis, ulcerative colitis, Chron's disease,...
Search relevance: 165.09 | Views last month: 3 -
Our goal in the present work was to determine whether male patients with untreated hypogonadism have an increased risk of developing rheumatic/autoimmune disease (RAD), and, if so, whether there...
Search relevance: 137.96 | Views last month: 2 -
The substantial progress in our understanding of molecular and cellular biology has allowed us to design biological therapeutics ('biologicals') with defined targets and effector functions. These...
Search relevance: 122.16 | Views last month: 1 -
Background The autoimmune thyroid diseases (AITDs), such as Graves' disease (GD) and Hashimoto's thyroiditis (HT), appear to develop as a result of complex interactions between...
Search relevance: 121.63 | Views last month: 0 -
Studies on immunological reconstitution after immune ablation and stem-cell therapy may yield important clues to our understanding of the pathogenesis of human autoimmune disease, due to the...
Search relevance: 116.70 | Views last month: 1 -
Proteomics technologies enable profiling of autoantibody responses using biological fluids derived from patients with autoimmune disease. They provide a powerful tool to characterize autoreactive...
Search relevance: 113.40 | Views last month: 11 -
We propose that the phenomenon of X-chromosome inactivation in females may constitute a risk factor for loss of T-cell tolerance; specifically that skewed X-chromosome inactivation in the thymus...
Search relevance: 109.98 | Views last month: 2 -
Treatment of rats suffering from florid chronic progressive systemic arthritis or from chronic remitting/relapsing encephalomyelitis with autologous bone marrow transplantation (BMT) is highly...
Search relevance: 109.18 | Views last month: 0 -
Inflammatory responses provoked by pathogens are antigen-specific in their induction but are nonspecific in their effects. Consequently, they are potentially damaging to the host that produces...
Search relevance: 102.70 | Views last month: 0 -
In the past 5 years, around 350 patients have received haematopoietic stem cell (HSC) transplantation for an autoimmune disease, with 275 of these registered in an international data base in Basel...
Search relevance: 95.31 | Views last month: 2 -
Cytokines play a critical role in regulating lymphoid cell responses to most antigenic stimuli, and it is therefore very likely that these molecules profoundly affect the pathogenesis of...
Search relevance: 75.89 | Views last month: 6 -
Compounds of formula (I) for clinical treatment of autoimmune diseases, inflammatory diseases, organ transplant rejection and malignant neoplasia. A pharmaceutical composition comprising a...
Search relevance: 72.37 | Views last month: 0 -
We are delighted to welcome you to the first printed issue ofArthritis Research, a publication that has already existed on the Internet for the last few months. This fact alone is an indication...
Search relevance: 67.02 | Views last month: 0 -
Relapsing polychondritis is an autoimmune disease in which an inappropriate immune response destroys cartilage. Cartilage of the ears, larynx and nose rather than spine and joint cartilage is...
Search relevance: 64.65 | Views last month: 0 -
As readers may already be aware, the NIH have declared a plan that invites any journal that wishes to participate to deposit non-peer-reviewed research into PubMed Central, the new central...
Search relevance: 54.76 | Views last month: 0 -
The diagnosis of rheumatoid arthritis (RA) is primarily based on clinical symptoms, so it is often difficult to diagnose RA in very early stages of the disease. A disease-specific autoantibody...
Search relevance: 54.54 | Views last month: 1 -
Anti-Golgi complex autoantibodies are found primarily in patients with Sjögren's syndrome and systemic lupus erythematosus, although they are not restricted to these diseases. Several Golgi...
Search relevance: 51.54 | Views last month: 0
