Found 126 datasets matching "b-cells".
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Normally the immune response is restricted to the peripheral secondary lymphoid organs. However, additional ectopic lymphoid tissue may develop at chronic sites of inflammation. In the synovium of...
Search relevance: 185.81 | Views last month: 0 -
In rheumatoid arthritis, T cells and B cells participate in the immune responses evolving in the synovial lesions. Interaction between T cells and B cells is probably antigen specific because...
Search relevance: 184.49 | Views last month: 0 -
B cells and B-cell/T-cell collaborations are instrumental in the pathophysiology of systemic lupus erythematosus (SLE). This commentary highlights in particular the newly discovered role of...
Search relevance: 168.88 | Views last month: 0 -
Background Bruton's tyrosine kinase (Btk) is essential for B cell development and function. Mutations of Btk elicit X-linked agammaglobulinemia in humans and X-linked immunodeficiency in...
Search relevance: 107.18 | Views last month: 0 -
In the present study 55 IgVH genes amplified from three different anatomical regions of a rheumatoid arthritis (RA) patient were analyzed, adding further information on synovial B-cell...
Search relevance: 96.04 | Views last month: 0 -
Background Growth inhibition by RPR-130401, a non-peptidomimetic farnesyltransferase inhibitor, was investigated without or with combined exposure to ionizing radiation in three human...
Search relevance: 95.30 | Views last month: 0 -
Files pertaining to data analyses performed and presented in the preprint, 'Porcine intestinal innate lymphoid cells and lymphocyte spatial context revealed through single-cell RNA sequencing' by...
Search relevance: 79.26 | Views last month: 0 -
In rheumatic diseases, autoantibody-producing cells of interest are often hidden in a polyclonal B-lymphocyte population. Immunoglobulin gene fingerprinting is a useful approach to screen for...
Search relevance: 76.57 | Views last month: 0 -
Background Lymphoid tissues constitute basic structures where specific immune responses take place. This leads to the development of germinal centres (GCs), migration of cells and the...
Search relevance: 56.64 | Views last month: 1 -
Background The immune system is particularly sensitive to stress. Although acute stress generally has positive effects, chronic stress typically provokes immunosuppression. The...
Search relevance: 51.03 | Views last month: 0 -
The influence of HLA DRB1 alleles on B-cell homeostasis was analyzed in 164 patients with rheumatoid arthritis (RA). The percentages of CD19+ B lymphocytes determined in the peripheral circulation...
Search relevance: 50.96 | Views last month: 0 -
Patients with Sjögren's syndrome (SS) have characteristic lymphocytic infiltrates of the salivary glands. To determine whether the B cells accumulating in the salivary glands of SS patients...
Search relevance: 50.91 | Views last month: 0 -
The present study was designed to analyze the level of B-cell clonal diversity in patients with rheumatoid arthritis by using HCDR3 (third complementarity determining region of the...
Search relevance: 50.85 | Views last month: 0 -
The data set is a matrix of cellular biochemical (metabolites) in HepG2 cells treated with various metal oxide nanomaterials composed of CeO2, SiO2 and CuO. This dataset is associated with the...
Search relevance: 49.20 | Views last month: 6 -
Differential expressed gene lists and altered canonical pathways in HepG2 cells after CeO2 particle treatment. This dataset is associated with the following publication: Thai, S., C. Jones, B....
Search relevance: 49.20 | Views last month: 1 -
Background Pneumocystis carinii causes pneumonia in immunocompromised patients with a high morbidity and mortality rate, but the interaction between this organism and the host cell is...
Search relevance: 48.22 | Views last month: 0 -
Dataset for 'Effects of multi-walled carbon nanotubes on gene and microRNA expression in human hepatocarcinoma HepG2 cells' by Sheau-Fung Thai et al., accepted by Materials Express. For the data...
Search relevance: 47.52 | Views last month: 0 -
Dominant paradigms for the understanding of rheumatoid arthritis (RA) pathogenesis have changed over the years. A predominant role of B lymphocytes, and perhaps of the rheumatoid factor they...
Search relevance: 47.42 | Views last month: 0 -
Background Cortical myosin-II filaments in Dictyostelium discoideum display enrichment in the posterior of the cell during cell migration and in the cleavage furrow during cytokinesis....
Search relevance: 47.23 | Views last month: 0 -
Data include RNA sequencing, cytokine levels, cytotoxicity responses and reactive oxygen species (ROS) levels in primary human brain microvascular endothelial cells (HBMEC) and an immortalized...
Search relevance: 47.16 | Views last month: 0
