Found 2036 datasets matching "bioactivity".
-
Read-across is a popular data gap filling technique within category and analogue approaches for regulatory purposes. Acceptance of read-across remains an ongoing challenge with several efforts...
Search relevance: 109.13 | Views last month: 0 -
The data set contains data for the following assays performed using 6PPD-quinone and/or 6PPD. 1) Larval fathead minnow transcriptomics; 2) larval fathead minnow EcoToxChips [6PPD-quinone only];...
Search relevance: 98.28 | Views last month: 1 -
Dataset consists of high throughput in vitro bioactivity data and exposure predictions from the U.S. EPA’s Toxicity and Exposure Forecaster (ToxCast and ExpoCast) project. This dataset is...
Search relevance: 97.69 | Views last month: 1 -
The ToxCast program has generated in vitro screening data on over a thousand chemicals to assess potential disruption of important biological processes and assist in hazard identification and...
Search relevance: 96.88 | Views last month: 0 -
Dataset for Jesse Rogers et al., 'Integrating Transcriptomic and Targeted New Approach Methodologies into a Tiered Framework for Chemical Bioactivity Screening' published in Environmental Health...
Search relevance: 95.65 | Views last month: 0 -
The files and .R scripts here are provided to aid in understanding and reproduction of the analyses in the submitted paper, "Examining the Utility of In Vitro Bioactivity as a Protective Point of...
Search relevance: 94.57 | Views last month: 0 -
The dataset is an excel spreadsheet containing the raw data used to generate the tables and figures in the manuscript. This dataset is associated with the following publication: Thompson, L., J....
Search relevance: 94.42 | Views last month: 0 -
Bioactivity data for p,p'-DDD and analogues from ToxCast assays conducted in liver cells were sourced from the EPA’s CompTox Chemistry Dashboard. The links also provide access to the ToxCast assay...
Search relevance: 91.88 | Views last month: 0 -
*********** Note to Josh Harrill- I don't have a copy of the final manuscript so could you please add the description of this dataset (just delete this comment and enter or cut and paste and then...
Search relevance: 91.35 | Views last month: 0 -
All of the code used to analyze and report the data as well as build confidence in the approach is available as a supplementary RMarkdown report, and a tool to derive PODBioactivity...
Search relevance: 91.31 | Views last month: 0 -
Dataset for Jurgelewicz, A. et al, 'Assessing the impact of in vitro xenobiotic metabolism on estrogenic chemical bioactivity in high-throughput profiling assays' published in Toxicology, Vol 517,...
Search relevance: 91.11 | Views last month: 0 -
In vitro bioactivity concentrations and chemical concentrations of estrogens, androgens, and glucocorticoids from a nationwide screen of United States stream water samples. In vitro bioassays...
Search relevance: 89.39 | Views last month: 0 -
In the present study, we adapted an existing phenotypic profiling assay (“Cell Painting”, (Bray et al., 2016)) to be compatible with in-house microfluidics capabilities for 384-well culture...
Search relevance: 86.98 | Views last month: 1 -
ToxCast bioactivity data and model predictions for the ER and AR pathways for p,p'-DDD and analogues
ToxCast bioactivity data and model predictions for the estrogen receptor (ER) and androgen receptor (AR) pathways were obtained from the inks provided. This dataset is associated with the...
Search relevance: 82.85 | Views last month: 1 -
We use a supervised machine learning strategy to systematically investigate the relative importance of study type, machine learning algorithm, and type of descriptor on predicting in vivo...
Search relevance: 57.22 | Views last month: 0 -
Thousands of chemicals are directly added to or come in contact with food, many of which have undergone little to no toxicological evaluation. The landscape of the food-relevant chemical universe...
Search relevance: 48.69 | Views last month: 2 -
This includes various EPA contract lab conducted studies using 2EHHB and referenced in a 2EHHB Review manuscript. Citation information for this dataset can be found in Data.gov's References section.
Search relevance: 48.32 | Views last month: 1 -
Ozone Exposure During Implantation Increases Serum Bioactivity in HTR-8/SVneo Trophoblasts data. This dataset is associated with the following publication: Miller, C., E. Stewart, S. Snow, W....
Search relevance: 44.98 | Views last month: 0 -
There are five different files for this dataset: 1. A dataset listing the reported functional uses of chemicals (FUse) 2. All 729 ToxPrint descriptors obtained from ChemoTyper for chemicals in...
Search relevance: 42.34 | Views last month: 6
