Found 22 datasets matching "bone-density".
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Background Bisphosphonates are indicated in the prevention and treatment of osteoporosis. However, bone mineral density (BMD) continues to decline in up to 15% of bisphosphonate users....
Search relevance: 150.84 | Views last month: 3 -
Backgroud Bone mineral density (BMD) is a marker of long-term estrogen exposure. BMD measurement has been used in this context to investigate the association of estrogen with breast...
Search relevance: 146.97 | Views last month: 3 -
Osteoporosis is associated with low bone mass and microarchitectural deterioration of bone tissue with clinical manifestation of low trauma fractures. Rheumatoid arthritis (RA) is a risk factor...
Search relevance: 105.29 | Views last month: 2 -
The use of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) to reduce serum cholesterol is well described. However, the recent finding that statins have direct effects on bone...
Search relevance: 94.94 | Views last month: 0 -
Background It has been reported that there is an inverse association between osteoarthritis (OA) and osteoporosis. However, the relationship of bone mass to OA in a Japanese population...
Search relevance: 87.63 | Views last month: 0 -
Background Hydroxymethylglutaryl coenzyme A reductase inhibitors increase new bone formation in vitro and in rodents. Results of epidemiologic analyses evaluating the association between...
Search relevance: 62.75 | Views last month: 1 -
During space flight bone mineral density is decreased by the influence of osteoclast activation which molecular mechanism is expectantly investigated. In the study of medaka bone development we...
Search relevance: 61.52 | Views last month: 0 -
During space flight bone mineral density is decreased by the influence of osteoclast activation which molecular mechanism is expectantly investigated. In the study of medaka bone development we...
Search relevance: 59.88 | Views last month: 0 -
Principles of magnetic resonance are employed to generate data, such as image intensity data, reflecting the spatial distribution of one or more isotopes carried in a solid-state specimen such as...
Search relevance: 59.49 | Views last month: 0 -
This study investigated the effects of a 14-day spaceflight on bone mass, density and microarchitecture in weight bearing (femur and humerus) and non-weight bearing (2nd) lumbar vertebra and...
Search relevance: 59.02 | Views last month: 0 -
Reduced skeletal loading leads to marked bone loss. Animal models of hindlimb suspension are widely used to assess alterations in skeleton during the course of complete unloading. More recently,...
Search relevance: 55.21 | Views last month: 0 -
Reduced skeletal loading leads to marked bone loss. Animal models of hindlimb suspension are widely used to assess alterations in skeleton during the course of complete unloading. More recently,...
Search relevance: 54.54 | Views last month: 0 -
Bone growth may occur in spaceflight as a response to skeletal unloading and head-ward fluid shifts. While unloading causes significant loss of bone mass and density in legs of animals exposed to...
Search relevance: 52.54 | Views last month: 0 -
We examined the effects of ~30 days of spaceflight on glycogen synthase kinase 3 (GSK3) content and inhibitory serine phosphorylation in murine muscle and bone samples from four separate missions...
Search relevance: 49.37 | Views last month: 0 -
Understanding the axis of the human microbiome and physiological homeostasis is an essential task in managing deep-space travel associated health risks. The NASA led Rodent Research 5 mission...
Search relevance: 47.01 | Views last month: 0 -
Background The identification of new methods of evaluating patients with osteoporotic fracture should focus on their usefulness in clinical situations such that they are easily measured...
Search relevance: 45.81 | Views last month: 1 -
Bone loss occurs when the cellular events of bone formation are quantitatively larger than bone formation. This manuscript discusses the measurement of bone loss, occurrence in the population,...
Search relevance: 43.03 | Views last month: 4 -
Background The autoimmune thyroid diseases (AITDs), such as Graves' disease (GD) and Hashimoto's thyroiditis (HT), appear to develop as a result of complex interactions between...
Search relevance: 40.60 | Views last month: 0 -
Current meter components data were collected from FIXED PLATFORMS from 22 February 1992 to 18 February 1993. Data were collected by the Science Applications, Inc. (SAI) in support of the Physical...
Search relevance: 21.04 | Views last month: 0 -
The accession contains microfiche data provided by the Canadian Fisheries and Oceans and taken from the Canadian Data Report of Hydrography and Sciences. The details of the data contained in the...
Search relevance: 11.14 | Views last month: 0