Found 43 datasets matching "breast-cancer".
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Background The contribution of BRCA1 and BRCA2 to the incidence of male breast cancer (MBC) in the United Kingdom is not known, and the importance of these genes in the increased risk of...
Search relevance: 255.57 | Views last month: 3 -
Background Iranian breast cancer patients are relatively younger than their Western counterparts. The objective of the present study was to investigate risk factors for breast cancer in...
Search relevance: 246.80 | Views last month: 5 -
Background We conducted the present study to determine whether breast cancer morphology is genetically determined. Methods Using the nationwide...
Search relevance: 246.47 | Views last month: 0 -
Background Information regarding the characteristics and health of women who do and do not attend for breast cancer screening is limited and representative data are difficult to obtain. ...
Search relevance: 213.51 | Views last month: 2 -
Background The relationship between breast cancer and organochlorine exposure is controversial and complex. As estrogen receptor positive and negative breast cancer may represent...
Search relevance: 212.78 | Views last month: 1 -
Background Drug resistance in breast cancer is a major obstacle to successful chemotherapy. In this study we used cDNA microarray technology to examine gene expression profiles obtained...
Search relevance: 186.57 | Views last month: 6 -
All data used for these analyses are publicly available, either through CPDat, ToxRefDB, or the CompTox Chemicals Dashboard. Script associated with these analyses are publicly available through...
Search relevance: 176.54 | Views last month: 5 -
Background Mutations in BRCA1 and BRCA2 account for approximately 50% of breast cancer families with more than four affected cases, whereas exonic mutations in p53, PTEN, CHK2 and ATM...
Search relevance: 146.89 | Views last month: 0 -
In order to explore the possible role of E-cadherin in familial cancer, 19 familial breast cancer patients, whose tumours demonstrated loss of heterozygosity (LOH) at the E-cadherin locus, were...
Search relevance: 142.59 | Views last month: 1 -
Raw data and figures for Bisphenol A activates EGFR and ERK promoting proliferation, tumor spheroid formation and resistance to EGFR pathway inhibition in estrogen receptor-negative inflammatory...
Search relevance: 141.98 | Views last month: 0 -
We examined the stage specificity and heterogeneity of 18p11 alterations in a series of tumors representing 96 microdissected samples. Significant loss of heterozygosity (LOH) (63%) was found,...
Search relevance: 140.27 | Views last month: 2 -
Background The purpose of this study was to use insurance claims and tumor registry data to examine determinants of breast conserving surgery (BCS) in women with early stage breast...
Search relevance: 136.15 | Views last month: 3 -
The dataset contains the number (volume) for 11 types of cancer (bladder, breast, brain, colon, esophagus, liver, lung, pancreas, prostate, rectum, and stomach) surgeries performed in California...
Search relevance: 131.22 | Views last month: 0 -
Germline mutations in the tumor suppressorPTENpredispose human beings to breast cancer, and genetic and epigenetic alterations ofPTENare also detected in sporadic human breast cancer....
Search relevance: 131.22 | Views last month: 0 -
Background Breast cancer is the most common female malignancy and a major cause of death in middle-aged women. So far, germline mutations in the BRCA1 and BRCA2 genes in patients with...
Search relevance: 129.68 | Views last month: 2 -
Background It is known that use of hormone replacement therapy (HRT) by postmenopausal women increases the risk of breast cancer. Method In this...
Search relevance: 127.66 | Views last month: 0 -
Background We previously identified and characterized a novel 55 kDa nuclear protein, termed nmt55/p54nrb, whose expression was decreased in a subset of human breast tumors. The...
Search relevance: 118.68 | Views last month: 0 -
Background One area of concern within the largely successful UK National Health Service breast screening programme is the relatively high proportion of women showing mammographic...
Search relevance: 110.50 | Views last month: 1 -
Background It is not known whether there are differences in the quality and recommendations between evidence-based (EB) and consensus-based (CB) guidelines. We used breast cancer...
Search relevance: 106.65 | Views last month: 1
