Found 14 datasets matching "cardiovascular-events".
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Three clinical trials have recently focused on the benefits of lipid-regulating therapy in populations with normocholesterolaemia and low high-density lipoprotein (HDL)-cholesterol. Two secondary...
Search relevance: 98.45 | Views last month: 1 -
Long-term treatment with angiotensin-converting enzyme inhibitors reduces post-infarction morbidity and mortality in patients with left ventricular (LV) systolic dysfunction or symptomatic heart...
Search relevance: 93.80 | Views last month: 0 -
The key question in hypertension research today is, "Does it matter how elevated blood pressure is lowered?" The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial...
Search relevance: 93.77 | Views last month: 1 -
Whether it matters how pressure is lowered has been debated since antihypertensive drugs proved to prevent cardiovascular events. However, in clinical trials, while the stroke benefit predicted by...
Search relevance: 92.64 | Views last month: 1 -
Background Doxazosin and its role as an antihypertensive agent have come under recent scrutiny as a result of the early termination of that treatment arm in ALLHAT. It is unclear why the...
Search relevance: 89.25 | Views last month: 0 -
Do we need clinical trials to test the ability of transdermal HRT to prevent coronary heart disease?
Postmenopausal hormone replacement therapy (HRT) with oral oestrogen was predicted to reduce coronary heart disease (CHD) risk by 50%. Randomized controlled trials show no such benefit, however,...
Search relevance: 47.23 | Views last month: 0 -
Large scale clinical trials demonstrate significant reductions in cardiovascular event rates with statin therapy. The observed benefit of statin therapy, however, may be larger in these trials...
Search relevance: 46.82 | Views last month: 1 -
Lipid disorders are associated with atherosclerotic vascular disease, and therapy is associated with a substantial reduction in cardiovascular events. Current approaches to the treatment of lipid...
Search relevance: 44.57 | Views last month: 1 -
Background Clinical events committees (CEC) are used routinely to adjudicate suspected end-points in cardiovascular trials, but little information has been published about the various...
Search relevance: 43.62 | Views last month: 0 -
Introduction Sildenafil (Viagra®) is one of the drugs used in the first line therapy of male erectile dysfunction (MED). We have recorded outcomes, adverse events and acceptability of...
Search relevance: 35.03 | Views last month: 0 -
The importance of low-density lipoprotein (LDL) control in the management of patients at high risk of cardiovascular events is unquestionable. The major statin trials have shown that the benefits...
Search relevance: 33.62 | Views last month: 1 -
Background Chlamydia pneumoniae antigens, nucleic acids, or intact organisms have been detected in human atheroma. However, the presence of antibody does not predict subsequent...
Search relevance: 32.30 | Views last month: 1 -
Studies have linked exposure to ultrafine particulate matter (PM) and adverse cardiovascular events. Particulate matter-induced oxidative stress is believed to be a key mechanism underlying...
Search relevance: 29.59 | Views last month: 1 -
Background: Adverse cardiovascular events have been linked with PM2.5 exposure obtained primarily from air quality monitors, which rarely co-locate with participant residences. Modeled PM2.5...
Search relevance: 28.35 | Views last month: 3
