Found 5 datasets matching "caspase-activation".
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Background A family of aspartate-specific cysteinyl proteases, named caspases, mediates programmed cell death, apoptosis. In this function, caspases are important for physiological...
Search relevance: 149.79 | Views last month: 0 -
Background Hypertensive nephrosclerosis is the second most common cause of end-stage renal failure in the United States. The mechanism by which hypertension produces renal failure is...
Search relevance: 62.57 | Views last month: 0 -
Background Growth of cancer cells results from the disturbance of positive and negative growth control mechanisms and the prolonged survival of these genetically altered cells due to the...
Search relevance: 47.08 | Views last month: 0 -
Background Xanthurenic acid is an endogenous product of tryptophan degradation by indoleamine 2,3-dioxygenase (IDO). We have previously reported that IDO is present in mammalian lenses,...
Search relevance: 46.14 | Views last month: 0 -
Background Maitotoxin (MTX) initiates cell death by sequentially activating 1) Ca2+ influx via non-selective cation channels, 2) uptake of vital dyes via formation of large pores, and 3)...
Search relevance: 45.01 | Views last month: 0
