• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background The cyclin-dependent kinase inhibitor p27Kip1 is essential for proper control of cell cycle progression. The levels of p27Kip1 are regulated by several mechanisms including...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

Whole seedlings of wild type (4d) and atm mutants (4d) have been analyzed after a gamma ray irradiation of 0.75h 1.5h 3h & 5h (time course). Roots of wt (4d) atm (3d) and atr (4d) mutants have...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

The matricellular protein thrombospondin 2 (TSP2) regulates a variety of cell–matrix interactions. A prominent feature of TSP2-null mice is increased microvascular density, particularly in...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background The aberrant cell-cycle progression of HIV-1-infected kidney cells plays a major role in the pathogenesis of HIV-associated nephropathy, however the mechanisms whereby HIV-1...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background Growth inhibition by RPR-130401, a non-peptidomimetic farnesyltransferase inhibitor, was investigated without or with combined exposure to ionizing radiation in three human...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background: Rat Nb2-11C lymphoma cells are dependent on prolactin for proliferation and are widely used to study prolactin signaling pathways. To investigate the role of this hormone in...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

With technological advancements, human's desire to explore space is growing and more people are staying longer at the international space station (ISS). The impact of microgravity on stem cells...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

Plants exhibit a robust transcriptional response to gamma radiation which includes the induction of transcripts required for homologous recombination and the suppression of transcripts that...

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• Organization: Department of the Interior
• Updated: 2021-01-27T00:00:00Z

The Savannah Harbor Expansion Project (SHEP) began in January 2015 with the purpose of deepening the Savannah Harbor federal shipping channel to allow access to larger shipping vessels (U.S. Army...

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