Found 10 datasets matching "cellular assays".
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This file contains the data on apoptosis, neurite outgrowth, synaptogenesis and proliferation. This dataset is associated with the following publication: Harrill, J., T. Freudenrich, K. Wallace,...
Search relevance: 148.66 | Views last month: 0 -
We combine cell assays and metabolomics to create a powerful tool, which emerges to elevate the identification of new control chemicals. We combined the use of bigheaded carp fry cell line with...
Search relevance: 58.60 | Views last month: 2 -
The US EPA’s ToxCast program is designed to assess chemical perturbations of molecular and cellular endpoints using a variety of high-throughput screening (HTS) assays. However, existing HTS...
Search relevance: 52.99 | Views last month: 0 -
Background Two-hybrid screening for proteins that interact with the core domain of human topoisomerase I identified two novel proteins, BTBD1 and BTBD2, which share 80% amino acid...
Search relevance: 47.60 | Views last month: 0 -
High-throughput screening for potential thyroid-disrupting chemicals requires a system of assays to capture multiple molecular-initiating events (MIEs) that converge on perturbed thyroid hormone...
Search relevance: 46.20 | Views last month: 0 -
Development of the neurovascular unit (NVU) is a complex, multistage process that requires orchestrated cell signaling mechanisms across several cell types and ultimately results in the formation...
Search relevance: 44.90 | Views last month: 1 -
Background Cellulose acetate phthalate (CAP), a promising candidate microbicide for prevention of sexual transmission of the human immunodeficiency virus type 1 (HIV-1) and other...
Search relevance: 41.12 | Views last month: 1 -
It is well established that microgravity exposure causes significant muscle weakness and atrophy via muscle unloading. On Earth, muscle unloading leads to a disproportionate loss in muscle force...
Search relevance: 39.33 | Views last month: 0 -
Background The cyclin-dependent kinase inhibitor p27Kip1 is essential for proper control of cell cycle progression. The levels of p27Kip1 are regulated by several mechanisms including...
Search relevance: 39.23 | Views last month: 0 -
Background Epstein-Barr virus (EBV) infects resting B-lymphocytes and transforms them into immortal proliferating lymphoblastoid cell lines (LCLs) in vitro. The transformed immunoblasts...
Search relevance: 37.38 | Views last month: 0