Found 98 datasets matching "cholesterol".
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Background The short-term cholesterol-lowering efficacy of plant stanol esters has been open to debate, and the data from different clinical studies with hypercholesterolemic subjects...
Search relevance: 134.15 | Views last month: 0 -
Treatment decisions related to disease prevention are often based on two conventional and related assumptions. First, an intervention-induced change in a surrogate marker (such as high-density...
Search relevance: 131.01 | Views last month: 0 -
Three clinical trials have recently focused on the benefits of lipid-regulating therapy in populations with normocholesterolaemia and low high-density lipoprotein (HDL)-cholesterol. Two secondary...
Search relevance: 128.27 | Views last month: 1 -
The Myocardial Ischemia Reduction with Acute Cholesterol Lowering (MIRACL) Trial tested the hypothesis that intensive lowering of cholesterol with atorvastatin (80 mg/day) initiated 24-96 h after...
Search relevance: 124.34 | Views last month: 0 -
Background Fermented milk products have been shown to affect serum cholesterol concentrations in humans. Kefir, a fermented milk product, has been traditionally consumed for its...
Search relevance: 123.93 | Views last month: 1 -
Background Cholesterol oxides, the oxygenated derivatives of cholesterol, have been shown to cause programmed cell death in a variety of cell types. Using N9 microglia, this study was...
Search relevance: 122.64 | Views last month: 0 -
The importance of low-density lipoprotein (LDL) control in the management of patients at high risk of cardiovascular events is unquestionable. The major statin trials have shown that the benefits...
Search relevance: 118.13 | Views last month: 1 -
In this study, using male Wistar and Wistar-derived Goto-Kakizaki (GK) rats, which exhibit a non-obese type-2 diabetes phenotype, we investigated whether two key metabolic stressors, type-2...
Search relevance: 117.91 | Views last month: 0 -
Background It is commonly agreed that people with a high blood LDL-cholesterol will have a higher risk of coronary artery disease (CAD) than people with low blood LDL-cholesterol. Due to...
Search relevance: 112.07 | Views last month: 2 -
Background Plasma lipases and lipid transfer proteins are involved in the generation and speciation of high density lipoproteins. In this study we have examined the influence of plasma...
Search relevance: 83.38 | Views last month: 0 -
The Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) study was the first trial to assess whether statins might be of clinical benefit in those with recently unstable...
Search relevance: 81.18 | Views last month: 3 -
Rheumatoid arthritis (RA) patients experience a markedly increased frequency of cardiovascular disease. We evaluated cardiovascular risk profiles in 79 RA patients and in 39 age-matched and...
Search relevance: 76.53 | Views last month: 0 -
Arteriosclerotic vascular disease manifests as heart disease, stroke, aortic aneurysms, and peripheral vascular disease, and is a growing problem world-wide. The preventive efforts made so far...
Search relevance: 76.47 | Views last month: 1 -
Background The suitability of the strain Rhodococcus erythropolis ATCC 25544 grown in a two-liter fermentor as a source of cholesterol oxidase has been investigated. The strain produces...
Search relevance: 74.08 | Views last month: 0 -
Of the associations between dietary elements and coronary artery disease (CAD), the greatest body of evidence deals with the beneficial effect of reducing the dietary intake of saturated fatty...
Search relevance: 70.61 | Views last month: 0 -
This data represents the age-adjusted prevalence of high total cholesterol, hypertension, and obesity among US adults aged 20 and over between 1999-2000 to 2017-2018. Notes: * All estimates are...
Search relevance: 69.22 | Views last month: 0 -
Background PROSPER was designed to investigate the benefits of treatment with pravastatin in elderly patients for whom a typical doctor might consider the prescription of statin therapy...
Search relevance: 66.76 | Views last month: 0 -
Background This study was designed to evaluate the effects of a 24-month period of moderate exercise on serum lipids in menopausal women. Methods ...
Search relevance: 65.81 | Views last month: 2 -
In this study, we investigated effects of inhaled ozone exposure and high-cholesterol diet (HCD) in healthy Wistar and Wistar-derived Goto-Kakizaki (GK) rats, a non-obese model of type 2 diabetes....
Search relevance: 54.93 | Views last month: 1 -
Background A short-term study was carried out using guinea pigs to determine the effects of Curcuma domestica on lipid composition in the serum and aorta. ...
Search relevance: 52.87 | Views last month: 0