Found 10 datasets matching "clinical-trial-design".
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Introduction Trials of complex health interventions often pose difficult methodologic challenges. The objective of this paper is to assess the extent to which the various development...
Search relevance: 83.23 | Views last month: 5 -
Background Agitated or violent patients constitute 10% of all emergency psychiatric treatment. Management guidelines, the preferred treatment of clinicians and clinical practice all...
Search relevance: 75.09 | Views last month: 0 -
This symposium provided a useful forum for the discussion of issues relating to the design and conduct of clinical trials. There is a need for greater awareness of the complexity of modern day...
Search relevance: 72.91 | Views last month: 0 -
In one of the biggest dilemmas facing cardiovascular clinical research, clinical trials are increasingly being required to show benefits on clinical end-points rather than surrogate end-points,...
Search relevance: 70.47 | Views last month: 0 -
Some problems with the quality of controlled clinical trials can be addressed by following these procedures: registering all trials at inception; using systematic reviews to inform the design of...
Search relevance: 68.52 | Views last month: 1 -
Background Limited information has been published regarding how specific processes for event adjudication can affect event rates in trials. We reviewed nonfatal myocardial infarctions...
Search relevance: 64.96 | Views last month: 1 -
A common problem in clinical trials is the missing data that occurs when patients do not complete the study and drop out without further measurements. Missing data cause the usual statistical...
Search relevance: 64.37 | Views last month: 0 -
Background About two thirds of adults suffer from backpain at some time during their life. In the emergency room many patients with acute back pain are treated with intravenous...
Search relevance: 63.40 | Views last month: 0 -
Background Whilst there is broad agreement on what constitutes high quality health care for people with diabetes, there is little consensus on the most efficient way of delivering it....
Search relevance: 59.06 | Views last month: 0 -
Background It is not uncommon to observe circulating tumor antigen-specific T lymphocytes in cancer patients despite a lack of significant infiltration and destruction of their tumors....
Search relevance: 54.83 | Views last month: 0
