Found 7 datasets matching "cytotoxic-effects".
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Background Acute Intermittent Porphyria is a genetic disorder of heme metabolism, characterized by increased levels of porphyrin precursors, δ-aminolevulinic acid (ALA) and...
Search relevance: 145.41 | Views last month: 0 -
Supplemental material for "Hughes MF, Clapper HM, Tedla G, Sowers TD, Rogers KR. Simulated gastric leachate of 3D printer metal-fill filaments induces cytotoxic effects in rat and human intestinal...
Search relevance: 141.08 | Views last month: 1 -
The present invention relates to 2,3-position modified epothilone derivatives, methods of preparation of the derivatives, and intermediates therefor. The compounds of the invention as 16-membered...
Search relevance: 61.82 | Views last month: 0 -
Previous work identified a ‘cytotoxic burst’ (CTB) phenomenon wherein large numbers of the ToxCast assays begin to respond at or near test chemical concentrations that elicit cytotoxicity, and a...
Search relevance: 44.31 | Views last month: 1 -
Background Tetracycline-regulated systems have been used to control the expression of heterologous genes in such diverse organisms as yeast, plants, flies and mice. Adaptation of this...
Search relevance: 40.04 | Views last month: 0 -
Organogenesis in the embryo involves cell differentiation and organization events that are unique to each tissue and organ and are susceptible to developmental toxicants. Animal models are the...
Search relevance: 34.21 | Views last month: 1 -
Chemical toxicity can arise from disruption of specific biomolecular functions or through more generalized cell stress and cytotoxicity-mediated processes. Here, concentration-dependent responses...
Search relevance: 29.85 | Views last month: 3
