Found 36 datasets matching "developmental toxicology".
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Dataset for article ‘Optimization of Human Neural Progenitor Cells for an Imaging-Based High-Throughput Phenotypic Profiling Assay for Developmental Neurotoxicity Screening’ published 02/16/2022...
Search relevance: 118.46 | Views last month: 0 -
The data presented here support the application of the Stemina devTOXqP platform for predictive toxicology and further demonstrate its value in ToxCast as a novel resource that can generate...
Search relevance: 114.87 | Views last month: 0 -
This dataset consists of data from in vitro developmental neurotoxicity new approach methodologies (DNT-NAMs). Assays include evaluations of proliferation, apoptosis, viability, neurite outgrowth,...
Search relevance: 107.36 | Views last month: 1 -
The systems map described in this manuscript for neurulation will set the stage for constructing mathematical models and computer simulation of neural tube closure for human-relevant AOPs and...
Search relevance: 103.66 | Views last month: 0 -
Morphogenetic events are driven by cell-generated physical forces and complex cellular dynamics. To improve our capacity to predict developmental effects from cellular alterations, we built a...
Search relevance: 96.69 | Views last month: 0 -
Table of contents Table S1 DNT inventory List of sources and associated data collected for the development of the Bayesian hierarchical model. Table S2 Data...
Search relevance: 88.88 | Views last month: 0 -
This dataset includes data used to generate Figures 4C, 5B, 5C, and 5D in Tal et al. Screening for angiogenic inhibitors in zebrafish to evaluate a predictive model for developmental vascular...
Search relevance: 66.43 | Views last month: 0 -
Data for O'Shaughnessy et al. 2023 - Bypassing the Brain Barriers: Upregulation of Serum miR-495 and miR-543-3p Reflects Thyroid-Mediated Developmental Neurotoxicity in the Rat. This dataset is...
Search relevance: 62.45 | Views last month: 2 -
This file contains data used to generate figures shown in Catron et al. Characterization of host toxicity and microbiota disruption in larval zebrafish following developmental exposure to BPA and...
Search relevance: 60.81 | Views last month: 0 -
A database of embryo-fetal developmental toxicity (EFDT) studies of 379 pharmaceutical compounds in rat and rabbit. This dataset is not publicly accessible because: this paper uses EPA public data...
Search relevance: 59.72 | Views last month: 0 -
Organogenesis in the embryo involves cell differentiation and organization events that are unique to each tissue and organ and are susceptible to developmental toxicants. Animal models are the...
Search relevance: 58.66 | Views last month: 1 -
This file contains the data on apoptosis, neurite outgrowth, synaptogenesis and proliferation. This dataset is associated with the following publication: Harrill, J., T. Freudenrich, K. Wallace,...
Search relevance: 58.23 | Views last month: 0 -
thyroid hormone from serum of rats exposed to goitrogen. Morphometry in brain. Behavioral data. This dataset is associated with the following publication: OShaughnessy, K., P. Kosian, J. Ford,...
Search relevance: 58.12 | Views last month: 0 -
The dataset comprises ten data tables as well as a contents table. Data tables provide information on RT-qPCR primers and assay conditions, significantly altered metabolites, canonical pathways,...
Search relevance: 57.70 | Views last month: 0 -
Dataset for "Degitz SJ, Degoey PP, Haselman JT, Olker JH, Stacy EH, Blanksma C, Meyer S, Mattingly KZ, Blackwell B, Opseth AS, Hornung MW. Evaluating potential developmental toxicity of...
Search relevance: 56.58 | Views last month: 0 -
The AOP concept was used to translate ToxCast high-throughput screening data into a ToxPi matrix of 1058 chemicals x 24 features ordered by predicted potential to disrupt angiogenesis. This...
Search relevance: 55.18 | Views last month: 0 -
R-language data files from "Carstens KE, Freudenrich T, Wallace K, Choo S, Carpenter A, Smeltz M, Clifton MS, Henderson WM, Richard AM, Patlewicz G, Wetmore BA, Paul Friedman K, Shafer T....
Search relevance: 54.79 | Views last month: 0 -
The data set contains data for the following assays performed using 6PPD-quinone and/or 6PPD. 1) Larval fathead minnow transcriptomics; 2) larval fathead minnow EcoToxChips [6PPD-quinone only];...
Search relevance: 53.29 | Views last month: 1 -
Severe thyroid hormone (TH) deprivation during development impairs neurogenesis throughout the brain. The hippocampus also maintains a capacity for neurogenesis throughout life which is reduced in...
Search relevance: 53.22 | Views last month: 1 -
Hypospadias is a developmental defect of urethral tube closure that has a complex etiology involving genetic and environmental factors, including anti-androgenic and estrogenic disrupting...
Search relevance: 52.94 | Views last month: 0
