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Found 2 datasets matching "dt40-cell-line".

Federal
Mutant loxP vectors for selectable marker recycle and conditional knock-outs
- Organization: U.S. Department of Health & Human Services
- Updated: 2025-09-06
Background Gene disruption by targeted integration of transfected constructs becomes increasingly popular for studies of gene function. The chicken B cell line DT40 has been widely used...
- html
Search relevance: 118.82 | Views last month: 0
Federal
A conditional form of Bruton's tyrosine kinase is sufficient to activate multiple downstream signaling pathways via PLC Gamma 2 in B cells
- Organization: U.S. Department of Health & Human Services
- Updated: 2025-09-06
Background Bruton's tyrosine kinase (Btk) is essential for B cell development and function. Mutations of Btk elicit X-linked agammaglobulinemia in humans and X-linked immunodeficiency in...
- html
Search relevance: 77.25 | Views last month: 0

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Mutant loxP vectors for selectable marker recycle and conditional knock-outs

A conditional form of Bruton's tyrosine kinase is sufficient to activate multiple downstream signaling pathways via PLC Gamma 2 in B cells