Found 16 datasets matching "enzyme-substrate".
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Background The human FHIT gene is inactivated early in the development of many human cancers and loss of Fhit in mouse predisposes to cancer while reintroduction of FHIT suppresses tumor...
Search relevance: 99.20 | Views last month: 0 -
The present invention pertains to a method for polynucleotide synthesis, comprising the steps of: (i) reacting a polynucleotide processive enzyme, e.g., a polymerase or TdT, with a nucleotide...
Search relevance: 70.69 | Views last month: 0 -
Background Antibody-directed enzyme prodrug therapy (ADEPT) is a promising new approach to deliver anticancer drugs selectively to tumor cells. In this approach, an enzyme is conjugated...
Search relevance: 63.25 | Views last month: 0 -
Background Seeds of the legume plant Lathyrus sativus, which is grown in arid and semi arid tropical regions, contain Diamino Propionic acid (DAP). DAP is a neurotoxin, which, when...
Search relevance: 58.67 | Views last month: 1 -
Background The acetamidase of Mycobacterium smegmatis is a highly inducible enzyme. Expression of this enzyme is increased 100-fold when the substrate acetamide is present. The...
Search relevance: 57.54 | Views last month: 0 -
This dataset includes soil properties and microbial data from lake margin soils throughout the Yukon Flats National Wildlife Refuge. Data include multiple lakes that are defined as either stable...
Search relevance: 54.32 | Views last month: 0 -
Background Vaccinia virus gene B1R encodes a serine/threonine protein kinase. In vitro this protein kinase phosphorylates ribosomal proteins Sa and S2 and vaccinia virus protein H5R,...
Search relevance: 53.03 | Views last month: 0 -
Background The hepadnaviral reverse transcriptase can synthesize DNA on its native RNA template within viral cores but it is usually unable to synthesize DNA employing exogenous nucleic...
Search relevance: 52.67 | Views last month: 0 -
Background Most test systems for acetylcholinesterase activity (E.C.3.1.1.7.) are using toxic inhibitors (BW284c51 and iso-OMPA) to distinguish the enzyme from butyrylcholinesterase...
Search relevance: 51.68 | Views last month: 0 -
Background Previous kinetic investigations of fungal-peroxidase catalyzed oxidation of N-aryl hydroxamic acids (AHAs) and N-aryl-N-hydroxy urethanes (AHUs) revealed that the rate of...
Search relevance: 45.72 | Views last month: 0 -
The key enzyme in coronavirus polyprotein processing is the viral main proteinase, Mpro, a protein with extremely low sequence similarity to other viral and cellular proteinases. Here, the crystal...
Search relevance: 45.20 | Views last month: 0 -
Our findings identified five structural categories of PFAS prone to metabolism. The metabolism pathways of PFAS are highly related to their structures and significantly impact their...
Search relevance: 40.98 | Views last month: 0 -
Background The hydrolysis of ATP and ADP by ecto-nucleoside triphosphate diphosphohydrolase 1 (CD39) requires divalent cations, like Ca2+ and Mg2+. In spite of considerable work, it is...
Search relevance: 40.09 | Views last month: 0 -
From 2017-2019, the Upper Midwest Environmental Sciences Center (UMESC) analyzed microcystin concentrations in samples collected from three different studies. The first study was on the movement...
Search relevance: 37.03 | Views last month: 0 -
High-throughput screening for potential thyroid-disrupting chemicals requires a system of assays to capture multiple molecular-initiating events (MIEs) that converge on perturbed thyroid hormone...
Search relevance: 31.86 | Views last month: 0 -
This data release includes six child items of soil and vegetation data from lake margin soils of the Yukon Flats National Wildlife Refuge, Alaska. Data includes multiple lakes that are defined as...
Search relevance: 31.50 | Views last month: 0
