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Found 5 datasets matching "erk-phosphorylation".

Federal
Inhibition of the MEK1/ERK pathway reduces arachidonic acid release independently of cPLA
- Organization: U.S. Department of Health & Human Services
- Updated: 2025-09-06
Background The 85-kDa cytosolic phospholipase A2 (cPLA2) mediates arachidonic acid (AA) release in MDCK cells. Although calcium and mitogen-activated protein kinases regulate cPLA2, the...
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Search relevance: 159.61 | Views last month: 0
Federal
Delta Opioid activation of the Mitogen-activated protein kinase cascade does not require transphosphorylation of Receptor Tyrosine Kinases
- Organization: U.S. Department of Health & Human Services
- Updated: 2025-09-06
Background In this study, we investigated the mechanism(s) by which delta opioids induce their potent activation of extracellular signal-regulated protein kinases (ERKs) in different...
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Search relevance: 151.73 | Views last month: 0
Federal
Inability of Serotonin to Activate the c-Jun N-terminal Kinase and p38 Kinase Pathways in Rat Aortic Vascular Smooth Muscle Cells
- Organization: U.S. Department of Health & Human Services
- Updated: 2025-09-06
Background Serotonin (5-HT, 5-hydroxytryptamine) activates the Extracellular Signal-Regulated Kinase (ERK)/ Mitogen-Activated Protein Kinase (MAPK) pathways, in vascular smooth muscle...
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Search relevance: 57.44 | Views last month: 0
Federal
A conditional form of Bruton's tyrosine kinase is sufficient to activate multiple downstream signaling pathways via PLC Gamma 2 in B cells
- Organization: U.S. Department of Health & Human Services
- Updated: 2025-09-06
Background Bruton's tyrosine kinase (Btk) is essential for B cell development and function. Mutations of Btk elicit X-linked agammaglobulinemia in humans and X-linked immunodeficiency in...
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Search relevance: 53.58 | Views last month: 0
Federal
Transcription profiling of human MCF10A cells subjected to ionizing radiation and treatment with transforming growth factor beta-1
- Organization: National Aeronautics and Space Administration
- Updated: 2025-08-21
Transforming growth factor beta-1 (TGFbeta) is a tumor suppressor during the initial stage of tumorigenesis, but it can switch to a tumor promoter during neoplastic progression. Ionizing radiation...
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Search relevance: 40.07 | Views last month: 1

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Inhibition of the MEK1/ERK pathway reduces arachidonic acid release independently of cPLA

Delta Opioid activation of the Mitogen-activated protein kinase cascade does not require transphosphorylation of Receptor Tyrosine Kinases

Inability of Serotonin to Activate the c-Jun N-terminal Kinase and p38 Kinase Pathways in Rat Aortic Vascular Smooth Muscle Cells

A conditional form of Bruton's tyrosine kinase is sufficient to activate multiple downstream signaling pathways via PLC Gamma 2 in B cells

Transcription profiling of human MCF10A cells subjected to ionizing radiation and treatment with transforming growth factor beta-1