Found 19 datasets matching "estrogens".
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This invention relates to novel pharmaceutical compositions and methods for their preparation containing conjugated estrogens for the treatment of peri-menopausal, menopausal and post-menopausal...
Search relevance: 117.76 | Views last month: 1 -
These five datasets document 1. physical and chemical soil properties for mesocosm soil that was collected from an experimental vegetated buffer strip plot; 2. Corrected final data for veterinary...
Search relevance: 66.19 | Views last month: 0 -
Disease outbreaks, skin lesions, fish kill events, and reproductive abnormalities have been observed in wild populations of bass in the Chesapeake Bay watershed. Occurrence of synthetic and...
Search relevance: 59.81 | Views last month: 0 -
This data describes the relative luminescence units and relative fluorescence units of lysates of two estrogen responsive chemically-activated luciferase expression human breast VM7Luc4E2 and...
Search relevance: 37.52 | Views last month: 0 -
The observational studies of hormone users are compromised by systematic biases that lead to an overestimation of benefit and an underestimation of risk. Studies of mechanism could support either...
Search relevance: 37.03 | Views last month: 1 -
In vitro bioactivity concentrations and chemical concentrations of estrogens, androgens, and glucocorticoids from a nationwide screen of United States stream water samples. In vitro bioassays...
Search relevance: 36.45 | Views last month: 0 -
There is significant concern regarding potential impairment of fish reproduction associated with endocrine disrupting chemicals. Aromatase (CYP19) is a steroidogenic enzyme involved in the...
Search relevance: 36.10 | Views last month: 1 -
Adult fathead minnows were exposed to dilutions of a historically estrogenic wastewater treatment plant effluent in a 21-d reproduction study. This dataset is comprised of a variety of endpoints...
Search relevance: 32.71 | Views last month: 0 -
Results of partial least squares (PLS) analysis of metabolite changes and contaminant concentrations to determine contaminants most likely to responsible for biological effects and to screen...
Search relevance: 32.30 | Views last month: 0 -
In vitro bioactivity concentrations and chemical concentrations of estrogens, androgens, and glucocorticoids from a pilot study of US tapwaters. In vitro bioassays include T47D-Kbluc, MDA-kb2, and...
Search relevance: 32.05 | Views last month: 1 -
Background Human immunodeficiency virus (HIV) infection continues to increase at alarming rates in drug abusers, especially in women. Drugs of abuse can cause long-lasting damage to the...
Search relevance: 31.98 | Views last month: 1 -
Background Recent evidence suggests that estrogens exert effects in different tissues throughout the body, and that the estrogen receptor β (ERβ) may be important for the action of...
Search relevance: 31.98 | Views last month: 0 -
Although endocrine disrupting compounds have been detected in wastewater and surface waters worldwide using a variety of in vitro effects-based screening tools, e.g. bioassays, few have examined...
Search relevance: 31.22 | Views last month: 0 -
Includes 1) list of genes in the STAT5b biomarker and 2) list of accession numbers for microarray datasets used in study. This dataset is associated with the following publication: Oshida, K.,...
Search relevance: 31.01 | Views last month: 0 -
This data set describes experiments that were conducted to investigate whether exposure of male fathead minnows to environmentally-relevant estrone concentrations would result in elevated plasma...
Search relevance: 30.65 | Views last month: 0 -
the data set contains the figures and tables from the publication in addition to the means, standard errors of the mean and the sample sizes used in each group for every experiment. the data set...
Search relevance: 28.10 | Views last month: 1 -
Feminization of male fish and the role of endocrine-active chemicals in this phenomenon has been an area of intense study for many years. Estrone (E1), a natural steroid, is found in aquatic...
Search relevance: 26.96 | Views last month: 1 -
This research was designed to evaluate whether a biologically-based computational model aligned with an adverse outcome pathway (AOP) could effectively predict animal (in vivo) responses to...
Search relevance: 24.60 | Views last month: 2 -
Disruption of steroidogenesis by environmental chemicals can result in altered hormone levels causing adverse reproductive and developmental effects. A high-throughput assay using H295R human...
Search relevance: 23.67 | Views last month: 0
