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Found 3 datasets matching "farnesyltransferase-inhibitor".

#1 Federal
The farnesyl transferase inhibitor RPR-130401 does not alter radiation susceptibility in human tumor cells with a K-Ras mutation in spite of large changes in ploidy and lamin B distribution
- Organization: U.S. Department of Health & Human Services
- Updated: 2025-09-06
Background Growth inhibition by RPR-130401, a non-peptidomimetic farnesyltransferase inhibitor, was investigated without or with combined exposure to ionizing radiation in three human...
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Search relevance: 116.66 | Views last month: 0
#2 Federal
Lonafarnib
- Organization: U.S. Department of Health & Human Services
- Updated: 2025-03-17
Zokinvy (lonafarnib) is a prescription oral capsule medication that acts as a farnesyltransferase inhibitor. It comes in 50mg and 75mg strengths and is manufactured by Sentynl Therapeutics, Inc....
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Search relevance: 85.36 | Views last month: 0
#3 Federal
Interaction between mevalonate pathway and retinoic acid-induced differentiation
- Organization: U.S. Department of Health & Human Services
- Updated: 2025-09-06
All trans retinoic acid (ATRA) is a potent inducer of differentiation of HL-60 cell line. The pretreatment of the cells by compactin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl (HMG)...
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Search relevance: 66.24 | Views last month: 0

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