Found 2 datasets matching "flavopiridol".
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Background Flavopiridol, a flavonoid currently in cancer clinical trials, inhibits cyclin-dependent kinases (CDKs) by competitively blocking their ATP-binding pocket. However, the...
Search relevance: 151.46 | Views last month: 0 -
Background The aberrant cell-cycle progression of HIV-1-infected kidney cells plays a major role in the pathogenesis of HIV-associated nephropathy, however the mechanisms whereby HIV-1...
Search relevance: 25.65 | Views last month: 0