Found 34 datasets matching "gene-families".
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Background Availability of genomewide information on an increasing but still limited number of plants offers the possibility of identifying orthologues, or related genes, in species with...
Search relevance: 189.20 | Views last month: 0 -
Background: Identification of orthologous relationships between genes from widely divergent taxa allows partial reconstruction of the gene complement of ancestral genomes. C2H2...
Search relevance: 183.93 | Views last month: 0 -
The emerging consensus regarding the origin of root nodule symbiosis (RNS), based on modeling of trait gain and loss across approximately 13,000 species within the “nitrogen-fixing clade” in the...
Search relevance: 100.84 | Views last month: 0 -
Background Cerebrovascular disease is the third leading cause of death in the United States, and about one-fourth of cerebrovascular deaths are attributed to ruptured intracranial...
Search relevance: 88.21 | Views last month: 0 -
Background To learn about the molecular etiology of strabismus, we are studying the genetic basis of 'congenital fibrosis of the extraocular muscles' (CFEOM). These syndromes are...
Search relevance: 56.14 | Views last month: 0 -
Background Analysis of cell-selective gene expression for families of proteins of therapeutic interest is crucial when deducing the influence of genes upon complex traits and disease...
Search relevance: 55.06 | Views last month: 0 -
Background The genome of Mycobacterium tuberculosis H37Rv has five copies of a cluster of genes known as the ESAT-6 loci. These clusters contain members of the CFP-10 (lhp) and ESAT-6...
Search relevance: 52.47 | Views last month: 0 -
The sequencing of genomes provides us with an inventory of the 'molecular parts' in nature, such as protein families and folds, and their functions in living organisms. The genomic occurrence of...
Search relevance: 48.58 | Views last month: 0 -
Genome-wide linkage analysis studies in families with systemic lupus erythematosus (SLE) have revealed consistent evidence of linkage to several regions of the genome. In a previous issue of this...
Search relevance: 47.42 | Views last month: 0 -
Background Congenital fibrosis of the extraocular muscles type 1 (CFEOM1) is an autosomal dominant eye movement disorder linked to the pericentromere of chromosome 12 (12p11.2 - q12)....
Search relevance: 46.89 | Views last month: 0 -
Background Annotations of completely sequenced genomes reveal that nearly half of the genes identified are of unknown function, and that some belong to uncharacterized gene families. To...
Search relevance: 46.42 | Views last month: 0 -
Background The availability of multiple complete genome sequences from diverse taxa prompts the development of new phylogenetic approaches, which attempt to incorporate information...
Search relevance: 46.40 | Views last month: 2 -
Background: Sodium bicarbonate cotransporter (NBC) genes encode proteins that execute coupled Na+ and HCO3- transport across epithelial cell membranes. We report the discovery,...
Search relevance: 45.83 | Views last month: 0 -
Background Celiac disease has a strong genetic association with HLA. However, this association only explains approximately half of the sibling risk for celiac disease. Therefore, other...
Search relevance: 44.08 | Views last month: 3 -
Background Mutations in the CHK2 gene at chromosome 22q12.1 have been reported in families with Li-Fraumeni syndrome. Chk2 is an effector kinase that is activated in response to DNA...
Search relevance: 43.15 | Views last month: 1 -
Contradictory lines of evidence have made it difficult to resolve the phylogenetic history of the legume diversification era; this is true for the backbone topology, and for the number and timing...
Search relevance: 42.87 | Views last month: 0 -
Background The honeybee (Apis mellifera) has been used with great success in a variety of behavioral studies. The lack of genomic tools in this species has, however, hampered efforts to...
Search relevance: 42.75 | Views last month: 1 -
The Virgin Galactic Unity 22 mission conducted the first astronaut-manipulated suborbital spaceflight experiment. The experiment examined the operationalization of Kennedy Space Center Fixation...
Search relevance: 42.48 | Views last month: 0 -
The synovial membrane (SM) of affected joints in ankylosing spondylitis (AS) is infiltrated by germinal center-like aggregates (foci) of lymphocytes similar to rheumatoid arthritis (RA). We...
Search relevance: 41.39 | Views last month: 1 -
Background The Master Catalog is a collection of evolutionary families, including multiple sequence alignments, phylogenetic trees and reconstructed ancestral sequences, for all...
Search relevance: 41.30 | Views last month: 2
