Found 74 datasets matching "gene-family".
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The present invention is broadly directed to therapeutic molecules capable of inter alia modulating apoptosis in mammalian cells. The therapeutic molecules of the present invention encompass...
Search relevance: 118.42 | Views last month: 1 -
Background Single-nucleotide polymorphisms (SNPs) are considered to be useful polymorphic markers for genetic studies of polygenic traits. Single-stranded conformational polymorphism...
Search relevance: 99.01 | Views last month: 0 -
Background Annotations of completely sequenced genomes reveal that nearly half of the genes identified are of unknown function, and that some belong to uncharacterized gene families. To...
Search relevance: 96.03 | Views last month: 0 -
Background The sequences encoding the yeast RNA polymerase II (RPB) subunits are single copy genes. Results While those characterized so far for the...
Search relevance: 91.08 | Views last month: 1 -
Background The availability of complete genome sequences enables all the members of a gene family to be identified without limitations imposed by temporal, spatial or quantitative...
Search relevance: 73.68 | Views last month: 0 -
Background Analysis of cell-selective gene expression for families of proteins of therapeutic interest is crucial when deducing the influence of genes upon complex traits and disease...
Search relevance: 58.33 | Views last month: 0 -
Background The human NOTCH4 gene is a candidate gene for schizophrenia due to its chromosomal location and neurobiological roles. In a British linkage study, NOTCH4 gene polymorphisms...
Search relevance: 54.41 | Views last month: 1 -
Background Availability of genomewide information on an increasing but still limited number of plants offers the possibility of identifying orthologues, or related genes, in species with...
Search relevance: 54.17 | Views last month: 0 -
Background Familial atrial fibrillation, an autosomal dominant disease, was previously mapped to chromosome 10q22. One of the genes mapped to the 10q22 region is DLG5, a member of the...
Search relevance: 52.48 | Views last month: 0 -
Background Homeobox genes of the orthodenticle (otd)/Otx family have conserved roles in the embryogenesis of head and brain. Gene replacement experiments show that the Drosophila otd...
Search relevance: 49.77 | Views last month: 0 -
TheTnfrh1gene (gene symbolTnfrsf23) is located near one end of a megabase-scale imprinted region on mouse distal chromosome 7, about 350 kb distant from the nearest known imprinting control...
Search relevance: 48.81 | Views last month: 0 -
Genome-wide transcriptional profiling showed that reducing gravity levels in the International Space Station (ISS) causes important alterations in Drosophila gene expression intimately linked to...
Search relevance: 47.49 | Views last month: 0 -
Background A partial cDNA clone from dog thyroid presenting a very significant similarity with an uncharacterized mouse EST sequence was isolated fortuitously. We report here the...
Search relevance: 47.07 | Views last month: 0 -
Genome-wide transcriptional profiling showed that reducing gravity levels in the International Space Station (ISS) causes important alterations in Drosophila gene expression intimately linked to...
Search relevance: 46.76 | Views last month: 0 -
Background The human genome contains at least 18 genes for Nudix hydrolase enzymes. Many have similar functions to one another. In order to understand their roles in cell physiology,...
Search relevance: 46.10 | Views last month: 0 -
Background The Apo-1/Fas (CD95) molecule is an apoptosis-signaling cell surface receptor belonging to the tumor necrosis factor (TNF) receptor family. Both Fas and Fas ligand (FasL) are...
Search relevance: 46.04 | Views last month: 0 -
Respiratory syncytial virus (RSV) and pneumonia virus of mice (PVM) are viruses of the family Paramyxoviridae, subfamily pneumovirus, which cause clinically important respiratory infections in...
Search relevance: 45.83 | Views last month: 0 -
Background To learn about the molecular etiology of strabismus, we are studying the genetic basis of 'congenital fibrosis of the extraocular muscles' (CFEOM). These syndromes are...
Search relevance: 45.81 | Views last month: 0 -
The invention relates to a process for the production of L-amino acids, in particular L-threonine, in which the following steps are carried out: a) fermentation of the microorganisms of the family...
Search relevance: 44.81 | Views last month: 1 -
The invention relates to a process for the preparation of L-amino acids, especially L-threonine, in which the following steps are carried out: a) fermentation of microorganisms of the family...
Search relevance: 44.42 | Views last month: 0
