Found 126 datasets matching "gene-function".
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Data generated to test nitrification inhibition of chromium. This dataset is associated with the following publication: Kapoor, V., M. Elk, X. Li, C. Impellitteri , and J. Santodomingo. Effects...
Search relevance: 106.08 | Views last month: 0 -
Background Transgenic mice have been used extensively to analyze gene function. Unfortunately, traditional transgenic procedures have only limited use in analyzing alleles that cause...
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Background The intrarenal natriuretic hormone dopamine (DA) is metabolised by catechol-O-methyltransferase (COMT) and monoamine oxidase (MAO). Inhibition of COMT, as opposed to MAO,...
Search relevance: 85.51 | Views last month: 0 -
The disease known as Septoria nodorum blotch, or SNB, is caused by a fungal pathogen that infects wheat plants and can cause substantial losses in grain yield. When a specific protein known as...
Search relevance: 65.36 | Views last month: 0 -
Background Nitrogen fixation gene expression in Sinorhizobium meliloti, the alfalfa symbiont, depends on a cascade of regulation that involves both positive and negative control. On top...
Search relevance: 51.17 | Views last month: 0 -
With extended stays aboard the International Space Station (ISS) becoming commonplace there is a need to better understand the effects of microgravity on cardiac function. We utilized human...
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Background The moss Physcomitrella patens is an attractive model system for plant biology and functional genome analysis. It shares many biological features with higher plants but has...
Search relevance: 48.91 | Views last month: 0 -
Background As more complete genomes are sequenced, conservation of gene order between different organisms is emerging as an informative property of the genomes. Conservation of gene...
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Cystic fibrosis is a genetic disease that is associated with abnormal sweat electrolytes, sino-pulmonary disease, exocrine pancreatic insufficiency, and male infertility. Insights into...
Search relevance: 48.55 | Views last month: 1 -
Amyotrophic lateral sclerosis (ALS) is a progressive lethal disorder of large motor neurons of the spinal cord and brain. In approximately 20% of the familial and 2% of sporadic cases the disease...
Search relevance: 47.66 | Views last month: 0 -
These supplementary data tables represent gene annotations, gene ontology terms (GO), and gene coordinates from the boll weevil (Anthonomus grandis grandis, Agg) reference genome that appear in...
Search relevance: 47.65 | Views last month: 0 -
The data in the Porcine Translational Research Database is supported by >5800 references, and contains 65 data fields for each entry, including >9700 full length (5′ and 3′) unambiguous pig...
Search relevance: 47.41 | Views last month: 1 -
The present invention is broadly directed to therapeutic molecules capable of inter alia modulating apoptosis in mammalian cells. The therapeutic molecules of the present invention encompass...
Search relevance: 47.25 | Views last month: 1 -
Background The ubiquitin-dependent protein degradation pathway is essential for the proteolysis of intracellular proteins and peptides. Deubiquitinating enzymes constitute a complex...
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Background Pneumocystis carinii causes pneumonia in immunocompromised patients with a high morbidity and mortality rate, but the interaction between this organism and the host cell is...
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Background: Classic methods of identifying genes involved in neural function include the laborious process of behavioral screening of mutagenized flies and then rescreening candidate...
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Physical forces greatly influence the growth and function of an organism. Altered gravity can perturb normal development and induce corresponding changes in gene expression. Understanding this...
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Background The rationale of using bovine papillomavirus-1 (BPV-1) derived vectors in gene therapy protocols lies in their episomal maintenance at intermediate to high copy number, and...
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Background Gene disruption by targeted integration of transfected constructs becomes increasingly popular for studies of gene function. The chicken B cell line DT40 has been widely used...
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Background Several lines of evidence strongly suggest that agouti-related peptide (AGRP) plays a key role in the regulation of metabolic function but ablation of the AGRP gene has no...
Search relevance: 45.32 | Views last month: 0
