Found 60 datasets matching "gene-identification".
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Background: Identification of orthologous relationships between genes from widely divergent taxa allows partial reconstruction of the gene complement of ancestral genomes. C2H2...
Search relevance: 122.78 | Views last month: 0 -
Dataset used in ORD-040059: Identification of Chemical Modulators of NF-κB Using a Gene Expression Biomarker Approach that includes publicaly available microarray datasets. This dataset is...
Search relevance: 114.79 | Views last month: 1 -
We examined molecular responses using transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 cGy, 1 GeV/nucleon (n) iron (56Fe) particles 1,...
Search relevance: 106.56 | Views last month: 0 -
We examined molecular responses using transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 cGy, 1 GeV/nucleon (n) proton (56Fe) particles...
Search relevance: 102.34 | Views last month: 0 -
The microarray experiments examined in the study. This dataset is associated with the following publication: Jackson, A., J. Liu, B. Vallanat, C. Jones, M. Nelms, G. Patlewicz, and J. Corton....
Search relevance: 100.81 | Views last month: 0 -
Background A partial cDNA clone from dog thyroid presenting a very significant similarity with an uncharacterized mouse EST sequence was isolated fortuitously. We report here the...
Search relevance: 89.82 | Views last month: 0 -
Background Cystinosis is an autosomal recessive disorder characterised by an intralysosomal accumulation of cystine, and affected individuals progress to end-stage renal failure before...
Search relevance: 88.86 | Views last month: 0 -
Parasitic helminths of the genusSchistosomamate, achieve sexual maturity and produce eggs in the bloodstream of their definitive hosts, and the most important pathological consequences of the...
Search relevance: 85.72 | Views last month: 0 -
Gene Expression Omnibus and ArrayExpress identification numbers of studies used in the analysis. This dataset is associated with the following publication: Cervantes, P., and C. Corton. A Gene...
Search relevance: 47.25 | Views last month: 0 -
The identification of the cystic fibrosis (CF) gene opened the way for gene therapy. In the ten years since then, proof of principle in vitro and then in animal models in vivo has been followed by...
Search relevance: 47.17 | Views last month: 2 -
Background Annotation of eukaryotic genomes is a complex endeavor that requires the integration of evidence from multiple, often contradictory, sources. With the ever-increasing amount...
Search relevance: 40.98 | Views last month: 0 -
Background DNA methyltransferases (MTases), unlike MTases acting on other substrates, exhibit sequence permutation. Based on the sequential order of the cofactor-binding subdomain, the...
Search relevance: 40.64 | Views last month: 0 -
Background We propose a new method for supervised learning from gene expression data. We call it 'tree harvesting'. This technique starts with a hierarchical clustering of genes, then...
Search relevance: 40.59 | Views last month: 0 -
We documented the type two polyketide synthases(PKS II) gene diversity and novelty by sequencing KSα genes known to synthesize bioactive small molecules. Sequences were derived from culturable...
Search relevance: 39.76 | Views last month: 0 -
Background We report the characterisation of the variable large protein (vlp) gene expressed by clinical isolate A1 of Borrelia recurrentis; the agent of the life-threatening disease...
Search relevance: 39.21 | Views last month: 0 -
Background Currently molecular diagnostic laboratories focus only on the identification of large deletion and duplication mutations (spanning one exon or more) for Duchenne Muscular...
Search relevance: 39.12 | Views last month: 0 -
Background The ability of Mycobacterium tuberculosis to survive and replicate in macrophages is crucial for the mycobacterium's ability to infect the host and cause tuberculosis. To...
Search relevance: 38.38 | Views last month: 0 -
Fathead minnows (Pimephales promelas) were exposed to 100 ug/L indomethacin, 200 ug/L ibuprofen, or 20 ug/L celecoxib for 96 h. Effects on cycloxygenase enzyme activity in ovary, prostaglandin...
Search relevance: 37.57 | Views last month: 2 -
Background Gene expression profiling among different tissues is of paramount interest in various areas of biomedical research. We have developed a novel method (DADA, Digital Analysis of...
Search relevance: 37.28 | Views last month: 1 -
Background Receptor protein tyrosine phosphatase rho (RPTPρ, gene symbol PTPRT) is a member of the type IIB RPTP family. These transmembrane molecules have been linked to signal...
Search relevance: 37.18 | Views last month: 0
