Found 6 datasets matching "glioblastoma".
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Background We have previously reported that glycerol acts as a chemical chaperone to restore the expression of WAF1 in some human cancer cell lines bearing mutant p53. Since the...
Search relevance: 116.98 | Views last month: 2 -
Background Intraoperative radiation therapy (IORT) is one of the methods used to deliver a large single dose to the tumor tissue while reducing the exposure of normal surrounding tissue....
Search relevance: 78.74 | Views last month: 0 -
Background It has been proposed that GL15, a human cell line derived from glioblastoma multiforme, is a possible astroglial-like cell model, based on the presence of cytoplasmic glial...
Search relevance: 63.72 | Views last month: 0 -
Background The p16INK4A gene product halts cell proliferation by preventing phosphorylation of the Rb protein. The p16INK4a gene is often deleted in human glioblastoma multiforme,...
Search relevance: 39.34 | Views last month: 1 -
The present invention provides a method of treating prostate cancer comprising administering to a patient in need thereof a therapeutically effective amount of a compound of the formula (I)...
Search relevance: 35.90 | Views last month: 0 -
Background Phosphatidylinositol-3,4,5-triphosphate (PtdInsP3) signaling is elevated in many tumors due to loss of the tumor suppressor PTEN, and leads to constitutive activation of Akt,...
Search relevance: 31.15 | Views last month: 0
