Found 12 datasets matching "granulocyte".
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A method of preparing a modified granulocyte colony stimulating factor (G-CSF) protein having reduced immunogenicity relative to human G-CSF comprises the steps of (i) identifying one or more...
Search relevance: 87.70 | Views last month: 0 -
Introduction Treatment of patients with severe sepsis with agents antagonising the effects of C5a has been proposed based on beneficial effects in animal experiments and in vitro studies...
Search relevance: 77.26 | Views last month: 0 -
Background The timed-sequential chemotherapy regimen consisting of etoposide, mitoxantrone and cytarabine (EMA) is an effective therapy for relapsed or refractory acute myelogenous...
Search relevance: 72.61 | Views last month: 0 -
This online resource provides supplementary items used to analyze data in the work, "Single-cell RNA sequencing characterization of Holstein cattle blood and milk immune cells during a chronic...
Search relevance: 71.09 | Views last month: 12 -
There is mounting evidence for a role of the growth factor granulocyte-macrophage colony-stimulating factor (GM-CSF) in inflammatory disease, including arthritis. In the present study, we examined...
Search relevance: 71.06 | Views last month: 0 -
Background: Haemodynamic instability is common in septic patients with acute renal failure. Continuous veno-venous haemodiafiltration (CVVHD) is therefore used as an alternative...
Search relevance: 42.10 | Views last month: 1 -
Bone-resorbing osteoclasts are formed from hemopoietic cells of the monocyte–macrophage lineage under the control of bone-forming osteoblasts. We have cloned an osteoblast-derived factor essential...
Search relevance: 37.39 | Views last month: 0 -
Background Typical symptoms and signs of a clinical condition may be absent in spinal cord injury (SCI) patients. Case presentation A male with...
Search relevance: 37.18 | Views last month: 2 -
The large surface area, good vascularization, immense capacity for solute exchange and ultra-thinness of the alveolar epithelium are unique features of the lung that can facilitate systemic...
Search relevance: 36.83 | Views last month: 0 -
Phosphoinositide 3-kinases (PI-3Ks) are enzymes that generate lipid second messenger molecules, resulting in the activation of multiple intracellular signalling cascades. These events regulate a...
Search relevance: 35.68 | Views last month: 0 -
Bone resorption in the joints is the characteristic finding in patients with rheumatoid arthritis (RA). Osteoclast-like cells are present in the synovial tissues and invade the bone of patients...
Search relevance: 31.13 | Views last month: 1 -
Introduction: Clinically useful predictions of end-organ function and failure in severe sepsis may be possible through analyzing the interactions among demographics, physiologic...
Search relevance: 23.30 | Views last month: 1
