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Found 3 datasets matching "hiv-1-reverse-transcriptase".

#1 Federal
Insertion of a small peptide of six amino acids into the β7–β8 loop of the p51 subunit of HIV-1 reverse transcriptase perturbs the heterodimer and affects its activities
- Organization: U.S. Department of Health & Human Services
- Updated: 2025-09-06
Background HIV-1 RT is a heterodimeric enzyme, comprising of the p66 and p51 subunits. Earlier, we have shown that the β7-β8 loop of p51 is a key structural element for RT dimerization...
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Search relevance: 221.31 | Views last month: 0
#2 Federal
Analysis of HIV-1 drug resistant mutations by line probe assay and direct sequencing in a cohort of therapy naive HIV-1 infected Italian patients
- Organization: U.S. Department of Health & Human Services
- Updated: 2025-09-06
Background The routine determination of drug resistance in newly HIV-1 infected individuals documents a potential increase in the transmission of drug-resistant variants. Plasma samples...
- html
Search relevance: 96.89 | Views last month: 0
#3 Federal
An algorithm for mapping positively selected members of quasispecies-type viruses
- Organization: U.S. Department of Health & Human Services
- Updated: 2025-09-06
Background Many RNA viruses do not have a single, representative genome but instead form a set of related variants that has been called a quasispecies. The sequence variability of such...
- html
Search relevance: 95.14 | Views last month: 0

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