• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background Loss or mutation of the mannose 6-phosphate/insulin-like growth factor-II receptor (M6P/IGF2R) has been found in breast cancer. However, whether or not decreased levels of...

• html

• Organization: U.S. Environmental Protection Agency
• Updated: 2017-03-01

Gene Expression Omnibus numbers only. This dataset is associated with the following publication: Mesnage, R., A. Phedonos, M. Arno, S. Balu, C. Corton, and M. Antoniou. Transcriptome profiling...

• xml

• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-29

Germline mutations in the tumor suppressorPTENpredispose human beings to breast cancer, and genetic and epigenetic alterations ofPTENare also detected in sporadic human breast cancer....

• html

• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background We previously identified and characterized a novel 55 kDa nuclear protein, termed nmt55/p54nrb, whose expression was decreased in a subset of human breast tumors. The...

• html

• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

We developed a mouse model that captures radiation effects on host biology by transplanting unirradiated Trp53 null mammary tissue to sham or irradiated hosts. Gene expression profiles of tumors...

• none
• none
• none

• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

The present invention is directed to the use of the extract of Ginkgo biloba leaves or isolated Ginkgolide B (GKB), a component of the extract of Ginkgo biloba leaves in a method for decreasing...

• html

• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background Structural requirements for the β1 integrin functions in cell adhesion, spreading and signaling have been well documented mainly for fibroblasts. In this study, we examined...

• html

• Organization: U.S. Environmental Protection Agency
• Updated: 2020-11-23

Sister Study is a prospective cohort of 50,884 U.S. women aged 35 to 74 years old conducted by the NIEHS. Eligible participants are women without a history of breast cancer but with at least one...

• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background The autoimmune thyroid diseases (AITDs), comprising Graves' disease (GD) and Hashimoto's thyroiditis (HT), appear to develop as a result of complex interactions between...

• html

• Organization: U.S. Environmental Protection Agency
• Updated: 2017-08-01

Population based cancer incidence rates were abstracted from National Cancer Institute, State Cancer Profiles for all available counties in the United States for which data were available. This is...

• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Tamoxifen, a potent anticancer agent known to interrupt the enhanced estrogen activity of malignant mammary gland cells, was recently approved by the Food and Drug Administration (FDA) for the...

• html