• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-01

The Virgin Galactic Unity 22 mission conducted the first astronaut-manipulated suborbital spaceflight experiment. The experiment examined the operationalization of Kennedy Space Center Fixation...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

['Spaceflight uniquely alters the physiology of both human cells and microbial pathogens, stimulating cellular and molecular changes directly relevant to infectious disease. However, the influence...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

With extended stays aboard the International Space Station (ISS) becoming commonplace there is a need to better understand the effects of microgravity on cardiac function. We utilized human...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

Immune dysregulation is among the main adverse outcomes of spaceflight. Despite its crucial role in host protection effects on the human antibody repertoire are unknown. Consequently we examined...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

Suborbital spaceflights now enable human-tended research investigating short-term gravitational effects in biological systems, eliminating the need for complex automation. Here, we discuss a...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

Microphysiological systems provide the opportunity to model accelerated changes at the human tissue level in the extreme space environment. Spaceflight-induced muscle atrophy experienced by...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

Microgravity or an altered gravity environment from the static 1g has been shown to influence global gene expression patterns and protein levels in cultured cells or animals, but it is unclear how...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

With technological advancements, human's desire to explore space is growing and more people are staying longer at the international space station (ISS). The impact of microgravity on stem cells...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

['The aim of the study was to continue of the proteomic data accumulation on the effects of space flight factors on the human body, including ground-based model experiments. Blood plasma samples...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

The BRIC-21 mission was designed to identify the response of Bacillus subtilis to the human spaceflight environment. For this mission, samples were grown in rich-medium using the Biological...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

['"Understanding physiologic reactions to weightlessness is an indispensable requirement for safe human space missions. While adaptations of human organ systems in response to weightlessness have...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

Efforts to understand the impact of spaceflight on the human body stem from growing interest in long-term space travel. Multiple organ systems are affected by microgravity and radiation, including...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

Given the limited knowledge of the biological impact of spaceflight, a multi-omics, systems biology approach was used to investigate NASA’s GeneLab data and astronaut biomedical profiles. These...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-07-14

A fully queryable REST API with JSON, XML, and CSV output as well as inline, runable examples using data from the transcriptional profiling and phenotypic characterization of the major human...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-07-14

A fully queryable REST API with JSON, XML, and CSV output as well as inline, runable examples using data from the transcriptional profiling and phenotypic characterization of the major human...

• html

• Organization: National Aeronautics and Space Administration
• Updated: 2025-07-14

A fully queryable REST API with JSON, XML, and CSV output as well as inline, runable examples using data from the transcriptional profiling and phenotypic characterization of the major human...

• html

• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

['Plants are primary producers of food and oxygen on Earth and will likewise be indispensable to the establishment of large-scale sustainable ecosystems and human survival in space. To contribute...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

Plants are primary producers of food and oxygen on Earth and will likewise be indispensable to the establishment of large-scale sustainable ecosystems and human survival in space. To contribute to...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

Physical forces associated with spaceflight and spaceflight analogue culture regulate a wide range of physiological responses by both bacterial and mammalian cells that can impact infection....

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-05-29

https://c3.nasa.gov/genelab/accession/GLDS-20/ This study presents the first global transcriptional profiling and phenotypic characterization of the major human opportunistic fungal pathogen,...

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