Found 9 datasets matching "immunogenicity".
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Background T helper epitopes are necessary for the induction of high titers of antigen-specific IgG antibodies. We are interested in the epitope modification of intact proteins as a...
Search relevance: 134.67 | Views last month: 0 -
A method of preparing a modified granulocyte colony stimulating factor (G-CSF) protein having reduced immunogenicity relative to human G-CSF comprises the steps of (i) identifying one or more...
Search relevance: 105.04 | Views last month: 0 -
This invention relates to a novel approach for identification of T-cell epitopes, that give rise to an immune reaction in a living host. By means of this novel method biological compounds can be...
Search relevance: 86.08 | Views last month: 0 -
This work is part of an experimental trial to develop and assess novel recombinant raccoonpox virus (RCN) rabies vaccines in the mouse model, for potential use in bats. Briefly, our research group...
Search relevance: 76.06 | Views last month: 0 -
The invention relates to the identification of epitopes for T-cells in human EPO as well as T-cell epitope peptides derived from EPO by means of which it is possible to create novel modified EPO...
Search relevance: 50.33 | Views last month: 0 -
High-pressure (HP) biotechnology is an emerging technique initially applied for food processing and more recently in pharmaceutical and medical sciences. Pressure can stabilize enzymes and...
Search relevance: 36.62 | Views last month: 1 -
Novel proteins of the Chicken Anemia Virus are described and compositions for preventing or treating infections with that virus (CAV), in particular vaccines less pathogenic than the CAV itself,...
Search relevance: 30.32 | Views last month: 0 -
This data set provides biological information from of a captive study of transgenic mice that received either passive serum transfers from black-footed ferrets (BFFs) that were vaccinated against...
Search relevance: 28.37 | Views last month: 0 -
Background The Gavac™ vaccine against the cattle tick Boophilus microplus has proven its efficacy in a large number of controlled and field experiments. However, this vaccine could be...
Search relevance: 26.14 | Views last month: 0