• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Introduction In this prospective, randomized controlled study, we aimed to evaluate the effect of IgM-enriched immunoglobulin treatment on progression of organ failure and septic shock...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

In rheumatic diseases, autoantibody-producing cells of interest are often hidden in a polyclonal B-lymphocyte population. Immunoglobulin gene fingerprinting is a useful approach to screen for...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

The present invention relates to a method for stabilizing chimeric immunoglobulins or immunoglobulin fragments. Furthermore, the invention also provides a stabilized anti-EGP-2 scFv fragment.

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

The role of autoantibodies in the etiology of autoimmune diseases remains unclear. However, an examination of the sequences of these autoantibodies can be informative. Antibody sequences that...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Patients with Sjögren's syndrome (SS) have characteristic lymphocytic infiltrates of the salivary glands. To determine whether the B cells accumulating in the salivary glands of SS patients...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background There have been many attempts to develop new materials with stability and high affinity towards immunoglobulins. Some of glycolipids such as gangliosides exhibit a high...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

Spaceflight is known to affect immune cell populations. In particular, splenic B-cell numbers decrease during spaceflight and in ground-based physiological models. Although antibody isotype...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background The possible participation of diesel exhaust inhalation during the fetal period in the elevation of IgE against pollen in postnatal life was investigated. ...

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• Organization: Department of Agriculture
• Updated: 2025-11-21

This entry contains all data and code required to reproduce the analysis of immune response data presented in the manuscript: Yeh, H.-Y., J. G. Frye, C. R. Jackson, Q. D. Read, J. E. Line, and A....

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

Spaceflight has been shown to suppress the adaptive immune response, altering the distribution and function of lymphocyte populations. B lymphocytes express highly specific and highly diversified...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

The present study was designed to analyze the level of B-cell clonal diversity in patients with rheumatoid arthritis by using HCDR3 (third complementarity determining region of the...

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• Organization: Department of the Interior
• Updated: 2023-04-05T00:00:00Z

This dataset represents 179 unique adult female northern elephant seals that were sampled between 2011 and 2021 during four different life history states (early breeding, late breeding, early...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background Diarrhoea caused by Escherichia coli is an important cause of infant morbidity and mortality in developing countries. Enteropathogenic Escherichia coli (EPEC) is considered...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-06-18

IgBLAST was developed at NCBI to facilitate analysis of immunoglobulin as well as T cell receptor (TR) sequences. It uses BLAST search algorithm.

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• Organization: Department of the Interior
• Updated: 2020-08-25T00:00:00Z

This metadata record represents passive immunity components of six songbird species (Passeriformes) in a single taxonomic family, the New World blackbirds (Icteridae). Six immune elements were...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background Experimental colitis with features similar to inflammatory bowel disease (IBD) has initially been described. A detailed analysis of inflammatory cells has not yet been...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background Polymorphisms in the gene that encodes the human cellular receptor for group B coxsackieviruses and adenoviruses (HCAR) could be responsible for differences in susceptibility...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Inflammatory cytokines may negatively influence contractility and contribute to the remodelling process in the failing myocardium. Traditional cardiovascular drugs appear to have little influence...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background Leukocyte Immunoglobulin-like Receptor-1 (LIR-1) and LIR-2 (also known as ILT2 and ILT4 respectively) are highly related cell surface receptors that bind a broad range of...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

IFN-γ was measured in supernatants after in vitro stimulation of peripheral blood mononuclear cells with collagen type II (CII), purified protein derivative or influenza virus. IFN-γ production in...

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