Found 7 datasets matching "indomethacin".
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Indomethacin is a prescription nonsteroidal anti-inflammatory drug (NSAID) available as 75 mg extended-release oral capsules. It works by inhibiting cyclooxygenase enzymes to reduce pain,...
Search relevance: 136.72 | Views last month: 0 -
Background It has been suggested that one aspect of non-steroidal anti-inflammatory drugs induced intestinal damage is due to either uncoupling of mitochondrial oxidative phosphorylation...
Search relevance: 89.39 | Views last month: 0 -
Fathead minnows (Pimephales promelas) were exposed to 100 ug/L indomethacin, 200 ug/L ibuprofen, or 20 ug/L celecoxib for 96 h. Effects on cycloxygenase enzyme activity in ovary, prostaglandin...
Search relevance: 42.51 | Views last month: 2 -
Background Endothelium dysfunction is believed to play a role in the development of cardiovascular disease. The aim of the present study was to evaluate the suitability of organ culture...
Search relevance: 38.45 | Views last month: 0 -
Background Extended culture of monocytes and fibroblasts in three-dimensional collagen gels leads to degradation of the gels (see linked study in this issue, "Fibroblasts and monocytes...
Search relevance: 31.16 | Views last month: 0 -
Background Cholesterol oxides, the oxygenated derivatives of cholesterol, have been shown to cause programmed cell death in a variety of cell types. Using N9 microglia, this study was...
Search relevance: 29.62 | Views last month: 0 -
The use of compounds of formula (I), or their salts, for the preparation of medicaments for the treatment of urinary incontinence, is new. A-X1-NO2 (I). A = R(COX)t; t = 0 or 1; X = O, NH or NR1c;...
Search relevance: 13.71 | Views last month: 0
