Found 21 datasets matching "interleukin-1".
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Interleukin-1 receptor antagonist (IL-1Ra) is a natural IL-1 inhibitor possessing anti-inflammatory properties. IL-1Ra is produced as different isoforms, one secreted (sIL-1Ra) and three...
Search relevance: 107.90 | Views last month: 0 -
Recent studies have described the spontaneous development of arthritis or vasculitis in IL-1 receptor antagonist (IL-1Ra) knockout mice bred on specific and different genetic backgrounds....
Search relevance: 82.19 | Views last month: 0 -
Background Helicobacter pylori is the main risk factor for the development of non-cardia gastric cancer. Increased proliferation of the gastric mucosa is a feature of H. pylori...
Search relevance: 79.01 | Views last month: 0 -
The transcription factors nuclear factor interleukin-6 (NF-IL6), early growth response-1 (EGR-1) and hypoxia-inducible factor-1 (HIF-1) have important roles in the molecular pathophysiology of...
Search relevance: 55.63 | Views last month: 0 -
This dataset represents 179 unique adult female northern elephant seals that were sampled between 2011 and 2021 during four different life history states (early breeding, late breeding, early...
Search relevance: 51.14 | Views last month: 0 -
Interleukin-4 (IL-4) mediates important pro-inflammatory functions in asthma including induction of the IgE isotype switch, expression of vascular cell adhesion molecule-1 (VCAM-1), promotion of...
Search relevance: 42.94 | Views last month: 0 -
Background: Haemodynamic instability is common in septic patients with acute renal failure. Continuous veno-venous haemodiafiltration (CVVHD) is therefore used as an alternative...
Search relevance: 42.20 | Views last month: 1 -
Giant cell arteritis (GCA) (temporal arteritis) and polymyalgia rheumatica (PMR) are common, frequently related conditions in people generally over 50 years of age. Most studies have shown an...
Search relevance: 41.89 | Views last month: 0 -
Tumor necrosis factor (TNF) and interleukin-1 (IL-1) are considered to be master cytokines in chronic, destructive arthritis. Therapeutic approaches in rheumatoid arthritis (RA) patients have so...
Search relevance: 40.78 | Views last month: 1 -
In our study we characterised the immunophenotype of monocytes that migrated through an endothelial cell (EC) monolayer in vitro. We found that monocyte migration led to an enhanced expression of...
Search relevance: 39.84 | Views last month: 0 -
A GeXP multiplex, RT-PCR assay was developed and optimized that simultaneously measures expression of a suite of immune-relevant genes in rainbow trout (Oncorhynchus mykiss), concentrating on...
Search relevance: 39.46 | Views last month: 0 -
Background HIV-1 is known to play a critical role in the pathogenesis of AIDS-associated Kaposi's sarcoma (KS). However, it remains controversial whether KS cells are target cells for...
Search relevance: 38.17 | Views last month: 1 -
Secretory leukocyte proteinase inhibitor and elafin are two low-molecular-mass elastase inhibitors that are mainly synthesized locally at mucosal sites. It is thought that their physicochemical...
Search relevance: 36.07 | Views last month: 0 -
This report concerns a clinical trial for rheumatoid arthritis (RA), approved by the US National Institutes of Health and the Food and Drug Administration. An amphotropic retrovirus (MFG-IRAP) was...
Search relevance: 34.10 | Views last month: 3 -
Background In addition to immune cells, many other cell types are known to produce cytokines. Cultured normal mouse gallbladder epithelial cells, used as a model system for gallbladder...
Search relevance: 33.71 | Views last month: 0 -
Background The development and activation of CD4+ helper T cell (Th) subsets with distinct patterns of unbalanced production of cytokines play an important part in infectious, allergic...
Search relevance: 33.01 | Views last month: 1 -
Background Respiratory syncytial virus (RSV) infection of airway epithelial cells stimulates the expression and secretion of a variety of cytokines including the chemotactic cytokines...
Search relevance: 32.76 | Views last month: 0 -
We developed a cell culture exposure system (CCES) to expose cells at the air-liquid interface (ALI) to volatile chemicals. We characterized the CCES by exposing indigo dye-impregnated filters...
Search relevance: 30.92 | Views last month: 0 -
Background Inhalation of Ascaris suum antigen by allergic monkeys causes an immediate bronchoconstriction and delayed allergic reaction, including a pulmonary inflammatory infiltrate. To...
Search relevance: 29.61 | Views last month: 0 -
Interleukin-11 (IL-11) is a pleiotropic cytokine that regulates the growth and development of hematopoietic stem cells and decreases the proinflammatory mediators of cytokine and nitric oxide...
Search relevance: 28.06 | Views last month: 1
