Found 8 datasets matching "intestinal-absorption".
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Background It is known that amino acid oxidation is increased in tumor-bearing rat muscles and that leucine is an important ketogenic amino acid that provides energy to the skeletal...
Search relevance: 215.20 | Views last month: 0 -
Background PKQuest, a new physiologically based pharmacokinetic (PBPK) program, is applied to human ethanol data. The classical definition of first pass metabolism (FPM) based on the...
Search relevance: 203.42 | Views last month: 1 -
The active hormonal form of vitamin D (1,25-dihydroxyvitamin D) is the primary regulator of intestinal calcium absorption efficiency. In vitamin D deficiency, intestinal calcium absorption is low...
Search relevance: 134.57 | Views last month: 0 -
Methods of controlling phosphate metabolism and metabolic acidosis in patients suffering from renal failure and associated hyperphosphatemia or patients predisposed to development of a...
Search relevance: 58.28 | Views last month: 1 -
Background It has been suggested that one aspect of non-steroidal anti-inflammatory drugs induced intestinal damage is due to either uncoupling of mitochondrial oxidative phosphorylation...
Search relevance: 56.27 | Views last month: 0 -
Background A "physiologically based pharmacokinetic" (PBPK) approach uses a realistic model of the animal to describe the pharmacokinetics. Previous PBPKs have been designed for specific...
Search relevance: 54.17 | Views last month: 1 -
Supplementary files for "Impact of gut permeability on estimation of oral bioavailability for chemicals in commerce and the environment"
Search relevance: 52.92 | Views last month: 0 -
Background The short-term cholesterol-lowering efficacy of plant stanol esters has been open to debate, and the data from different clinical studies with hypercholesterolemic subjects...
Search relevance: 38.45 | Views last month: 0
