Found 27 datasets matching "ischemic".
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Background Family history and twins studies suggest an inherited component to ischemic stroke risk. Candidate gene association studies have been performed but have limited capacity to...
Search relevance: 150.26 | Views last month: 0 -
This dataset contains risk-adjusted 30-day mortality and 30-day readmission rates, quality ratings, and number of deaths / readmissions and cases for ischemic stroke treated in California...
Search relevance: 128.19 | Views last month: 0 -
Background Oxidative stress plays a major role in the biochemical and pathological changes associated with myocardial ischemic-reperfusion injury (IRI). The need to identify agents with...
Search relevance: 127.59 | Views last month: 0 -
Background These studies investigate the role of mitoKATP channels, protein kinase C (PKC) and Mitogen activated protein kinase (p38MAPK) on the cardioprotection of ischemic (IP) and...
Search relevance: 92.88 | Views last month: 0 -
Cell transplantation to repair or regenerate injured myocardium is a new frontier in the treatment of cardiovascular disease. Even though it is based on many years of pre-clinical studies, much...
Search relevance: 86.63 | Views last month: 2 -
In light of the slow progress in developing effective therapies for ischemic stroke, magnetic resonance imaging techniques have emerged as new tools in stroke clinical trials. Rapid imaging with...
Search relevance: 77.16 | Views last month: 2 -
Background Inflammatory reactions occurring in the brain after ischemia may contribute to secondary damage. In the present study, effects of minocycline, an anti-inflammatory agent,...
Search relevance: 73.24 | Views last month: 0 -
The identification of angiogenic growth factors, such as vascular endothelial growth factor and fibroblast growth factor, has fueled interest in using such factors to induce therapeutic...
Search relevance: 68.63 | Views last month: 0 -
The mission of the VA Clinical Assessment Reporting and Tracking (CART) Program for cardiac catheterization laboratories (CART-CL) is to support a national VA reporting system, data repository,...
Search relevance: 64.59 | Views last month: 8 -
Background Brain death is strictly defined medically and legally. This diagnosis depends on three cardinal neurological features: coma, absent brainstem reflexes, and apnea. The...
Search relevance: 62.81 | Views last month: 0 -
Background During the first days after stroke, one to two fifths of the patients develop fever or subfebrile temperatures. Body temperature is a strong prognostic factor after stroke....
Search relevance: 56.18 | Views last month: 0 -
Background Lower limb paralysis occurs in 11% of patients after surgical procedure of thoracic or thoracoabdominal aneurysms and is an unpredictable and distressful complication. The aim...
Search relevance: 53.21 | Views last month: 1 -
Background Morphological and electrophysiological studies of ischemic muscles in peripheral arterial disease disclosed evidence of denervation and fibre atrophy. The purpose of the...
Search relevance: 51.72 | Views last month: 0 -
Inhibition of the sodium-hydrogen exchanger (NHE) is a powerful experimental tool to inhibit sodium and calcium accumulation within the ischemic myocyte and halt progression of cell ischemia to...
Search relevance: 43.20 | Views last month: 0 -
Background Existing animal models provide only indirect information about the pathogenesis of infections caused by indigenous gastrointestinal microflora and the kinetics of bacterial...
Search relevance: 36.76 | Views last month: 0 -
An explanation for the higher incidence of cardiovascular disease and heart failure in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) with doxazosin and...
Search relevance: 35.19 | Views last month: 0 -
Objective To assess the effects of a 6-month angiotensin-converting enzyme (ACE) inhibitor intervention on myocardial ischaemia. Method We...
Search relevance: 31.05 | Views last month: 3 -
The cornerstone in clinical evidence of the relative efficacy of thienopyridines (clopidogrel, ticlopidine) versus aspirin in the secondary prevention of vascular disease is the Clopidogrel versus...
Search relevance: 30.69 | Views last month: 0 -
The Intravenous Magnesium Efficacy in Acute Stroke (IMAGES) trial is a multicentre,randomised, placebo-controlled trial of magnesium sulphate (MgSO4) funded by the UK Medical Research Council....
Search relevance: 29.72 | Views last month: 1 -
Background GPIIb/IIIa inhibitors abciximab and eptifibatide have been shown to inhibit platelet aggregation in ischemic heart disease. Our aim was to test the efficacy of abiciximab (Reo...
Search relevance: 26.33 | Views last month: 0